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    WNK3 WNK lysine deficient protein kinase 3 [ Equus caballus (horse) ]

    Gene ID: 100060479, updated on 17-Aug-2024

    Summary

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    Official Symbol
    WNK3provided by VGNC
    Official Full Name
    WNK lysine deficient protein kinase 3provided by VGNC
    Primary source
    VGNC:VGNC:108141
    See related
    Ensembl:ENSECAG00000050691
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) X NC_009175.3 (44129799..44298780)

    Chromosome X - NC_009175.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111771490 Neighboring gene FYVE, RhoGEF and PH domain containing 1 Neighboring gene TSR2 ribosome maturation factor Neighboring gene uncharacterized LOC102148059 Neighboring gene family with sequence similarity 120 member C Neighboring gene NHP2-like protein 1 pseudogene Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009175.3 Chromosome X Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables potassium channel inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase WNK3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009175.3 Reference EquCab3.0 Primary Assembly

      Range
      44129799..44298780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023633604.1 → XP_023489372.1  serine/threonine-protein kinase WNK3 isoform X1

      UniProtKB/TrEMBL
      H9H031
      Conserved Domains (2) summary
      cd14031
      Location:136 → 410
      STKc_WNK3; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 3
      pfam12202
      Location:426 → 463
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal

    2. XM_023633601.1 → XP_023489369.1  serine/threonine-protein kinase WNK3 isoform X1

      UniProtKB/TrEMBL
      H9H031
      Related
      ENSECAP00000022946.4, ENSECAT00000029022.4
      Conserved Domains (2) summary
      cd14031
      Location:136 → 410
      STKc_WNK3; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 3
      pfam12202
      Location:426 → 463
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal

    3. XM_023633602.1 → XP_023489370.1  serine/threonine-protein kinase WNK3 isoform X1

      UniProtKB/TrEMBL
      H9H031
      Conserved Domains (2) summary
      cd14031
      Location:136 → 410
      STKc_WNK3; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 3
      pfam12202
      Location:426 → 463
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal

    4. XM_023633605.1 → XP_023489373.1  serine/threonine-protein kinase WNK3 isoform X2

      Conserved Domains (2) summary
      cd14031
      Location:136 → 410
      STKc_WNK3; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 3
      pfam12202
      Location:426 → 463
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal

    5. XM_023633603.1 → XP_023489371.1  serine/threonine-protein kinase WNK3 isoform X1

      UniProtKB/TrEMBL
      H9H031
      Conserved Domains (2) summary
      cd14031
      Location:136 → 410
      STKc_WNK3; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 3
      pfam12202
      Location:426 → 463
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal
    Nucleotide Protein
    Heading Accession and Version

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