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    RACGAP1 Rac GTPase activating protein 1 [ Equus caballus (horse) ]

    Gene ID: 100059818, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RACGAP1provided by VGNC
    Official Full Name
    Rac GTPase activating protein 1provided by VGNC
    Primary source
    VGNC:VGNC:22140
    See related
    Ensembl:ENSECAG00000010821
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See RACGAP1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 6 NC_009149.3 (68520441..68546856, complement)

    Chromosome 6 - NC_009149.3Genomic Context describing neighboring genes Neighboring gene aquaporin 5 Neighboring gene aquaporin 6 Neighboring gene acid sensing ion channel subunit 1 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009149.3 Chromosome 6 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic spindle midzone assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of centralspindlin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cleavage furrow IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle midzone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rac GTPase-activating protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009149.3 Reference EquCab3.0 Primary Assembly

      Range
      68520441..68546856 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005611153.3 → XP_005611210.1  rac GTPase-activating protein 1 isoform X2

      See identical proteins and their annotated locations for XP_005611210.1

      UniProtKB/TrEMBL
      A0A9L0S9W9, A0A9L0SHT9
      Related
      ENSECAP00000071647.1, ENSECAT00000086857.1
      Conserved Domains (3) summary
      cd04382
      Location:346 → 539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13 → 105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285 → 338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

    2. XM_001504234.6 → XP_001504284.1  rac GTPase-activating protein 1 isoform X2

      See identical proteins and their annotated locations for XP_001504284.1

      UniProtKB/TrEMBL
      A0A9L0S9W9, A0A9L0SHT9
      Conserved Domains (3) summary
      cd04382
      Location:346 → 539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13 → 105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285 → 338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

    3. XM_023643521.1 → XP_023499289.1  rac GTPase-activating protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A9L0S9W9, A0A9L0SHT9
      Conserved Domains (3) summary
      cd04382
      Location:346 → 539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13 → 105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285 → 338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

    4. XM_005611154.3 → XP_005611211.1  rac GTPase-activating protein 1 isoform X2

      See identical proteins and their annotated locations for XP_005611211.1

      UniProtKB/TrEMBL
      A0A9L0S9W9, A0A9L0SHT9
      Conserved Domains (3) summary
      cd04382
      Location:346 → 539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13 → 105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285 → 338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

    5. XM_023643522.1 → XP_023499290.1  rac GTPase-activating protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A9L0S9W9, A0A9L0SHT9
      Related
      ENSECAP00000073573.1, ENSECAT00000090433.1
      Conserved Domains (3) summary
      cd04382
      Location:346 → 539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13 → 105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285 → 338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

    6. XM_023643519.1 → XP_023499287.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A9L0RDH2, A0A9L0SHT9
      Related
      ENSECAP00000060548.1, ENSECAT00000130386.1
      Conserved Domains (3) summary
      cd04382
      Location:367 → 560
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:14 → 126
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:306 → 359
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

    7. XM_023643523.1 → XP_023499291.1  rac GTPase-activating protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A9L0S9W9, A0A9L0SHT9
      Conserved Domains (3) summary
      cd04382
      Location:346 → 539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13 → 105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285 → 338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    Nucleotide Protein
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