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    GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 [ Equus caballus (horse) ]

    Gene ID: 100059571, updated on 7-Sep-2024

    Summary

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    Official Symbol
    GABRG2provided by VGNC
    Official Full Name
    gamma-aminobutyric acid type A receptor subunit gamma2provided by VGNC
    Primary source
    VGNC:VGNC:18202
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See GABRG2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 14 NC_009157.3 (17013574..17054365, complement)

    Chromosome 14 - NC_009157.3Genomic Context describing neighboring genes Neighboring gene cyclin G1 Neighboring gene uncharacterized LOC111767739 Neighboring gene gamma-aminobutyric acid type A receptor subunit alpha1 Neighboring gene gamma-aminobutyric acid type A receptor subunit alpha6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009157.3 Chromosome 14 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GABA-A receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GABA-gated chloride ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables benzodiazepine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables inhibitory extracellular ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in gamma-aminobutyric acid signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, GABAergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of GABA-A receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendrite membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gamma-aminobutyric acid receptor subunit gamma-2; gamma-aminobutyric acid type A receptor subunit gamma2
    Names
    gamma-aminobutyric acid type A receptor gamma2 subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001433549.1 → NP_001420478.1  gamma-aminobutyric acid type A receptor subunit gamma2 precursor

      Status: VALIDATED

      Source sequence(s)
      CM084044

    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009157.3 Reference EquCab3.0 Primary Assembly

      Range
      17013574..17054365 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023617280.1 → XP_023473048.1  gamma-aminobutyric acid receptor subunit gamma-2

      Conserved Domains (1) summary
      pfam02931
      Location:69 → 251
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials