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    EHMT2 euchromatic histone lysine methyltransferase 2 [ Equus caballus (horse) ]

    Gene ID: 100059118, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EHMT2provided by VGNC
    Official Full Name
    euchromatic histone lysine methyltransferase 2provided by VGNC
    Primary source
    VGNC:VGNC:50590
    See related
    Ensembl:ENSECAG00000001546
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See EHMT2 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 20 NC_009163.3 (32472580..32485966, complement)

    Chromosome 20 - NC_009163.3Genomic Context describing neighboring genes Neighboring gene neuraminidase 1 Neighboring gene solute carrier family 44 member 4 Neighboring gene zinc finger and BTB domain containing 12 Neighboring gene complement C2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009163.3 Chromosome 20 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3K9 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables p53 binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-lysine dimethylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone-lysine N-methyltransferase EHMT2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009163.3 Reference EquCab3.0 Primary Assembly

      Range
      32472580..32485966 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023624650.1 → XP_023480418.1  histone-lysine N-methyltransferase EHMT2 isoform X5

      UniProtKB/TrEMBL
      A0A9L0RR64
      Related
      ENSECAP00000049065.2, ENSECAT00000078440.2
      Conserved Domains (7) summary
      smart00468
      Location:890 → 989
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1005 → 1127
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd00204
      Location:653 → 772
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:752 → 782
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:621 → 682
      Ank_2; Ankyrin repeats (3 copies)
      cl26247
      Location:144 → 297
      DNA_pol3_delta2; DNA polymerase III, delta subunit
      cl26464
      Location:50 → 206
      Atrophin-1; Atrophin-1 family

    2. XM_023624649.1 → XP_023480417.1  histone-lysine N-methyltransferase EHMT2 isoform X4

      UniProtKB/TrEMBL
      A0A9L0RR64
      Related
      ENSECAP00000065089.1, ENSECAT00000137920.1
      Conserved Domains (7) summary
      smart00468
      Location:924 → 1023
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1039 → 1161
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd00204
      Location:687 → 806
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:786 → 816
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:655 → 716
      Ank_2; Ankyrin repeats (3 copies)
      cl26247
      Location:144 → 297
      DNA_pol3_delta2; DNA polymerase III, delta subunit
      cl26464
      Location:50 → 206
      Atrophin-1; Atrophin-1 family

    3. XM_023624648.1 → XP_023480416.1  histone-lysine N-methyltransferase EHMT2 isoform X3

      UniProtKB/TrEMBL
      A0A9L0RR64
      Conserved Domains (7) summary
      smart00468
      Location:947 → 1046
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1062 → 1184
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd00204
      Location:710 → 829
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:809 → 839
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:678 → 739
      Ank_2; Ankyrin repeats (3 copies)
      cl26247
      Location:201 → 354
      DNA_pol3_delta2; DNA polymerase III, delta subunit
      cl26464
      Location:46 → 263
      Atrophin-1; Atrophin-1 family

    4. XM_023624646.1 → XP_023480414.1  histone-lysine N-methyltransferase EHMT2 isoform X1

      UniProtKB/TrEMBL
      A0A9L0RR64
      Conserved Domains (7) summary
      smart00468
      Location:981 → 1080
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1096 → 1218
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd00204
      Location:744 → 863
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:843 → 873
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:712 → 773
      Ank_2; Ankyrin repeats (3 copies)
      cl26247
      Location:201 → 354
      DNA_pol3_delta2; DNA polymerase III, delta subunit
      cl26464
      Location:46 → 263
      Atrophin-1; Atrophin-1 family

    5. XM_023624647.1 → XP_023480415.1  histone-lysine N-methyltransferase EHMT2 isoform X2

      UniProtKB/TrEMBL
      A0A9L0RR64, F6QBA4
      Related
      ENSECAP00000003787.3, ENSECAT00000005385.3
      Conserved Domains (6) summary
      smart00468
      Location:951 → 1050
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1066 → 1188
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd00204
      Location:714 → 833
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:813 → 843
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:682 → 743
      Ank_2; Ankyrin repeats (3 copies)
      cl26464
      Location:46 → 263
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein
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