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    ECE2 endothelin converting enzyme 2 [ Equus caballus (horse) ]

    Gene ID: 100059042, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ECE2provided by VGNC
    Official Full Name
    endothelin converting enzyme 2provided by VGNC
    Primary source
    VGNC:VGNC:17402
    See related
    Ensembl:ENSECAG00000015238
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human all
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    Genomic context

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    See ECE2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 19 NC_009162.3 (24941740..24971770)

    Chromosome 19 - NC_009162.3Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily F member 3 Neighboring gene von Willebrand factor A domain containing 5B2 Neighboring gene ALG3 alpha-1,3- mannosyltransferase Neighboring gene calcium/calmodulin dependent protein kinase II inhibitor 2 Neighboring gene proteasome 26S subunit ubiquitin receptor, non-ATPase 2 Neighboring gene small nucleolar RNA SNORD66 Neighboring gene eukaryotic translation initiation factor 4 gamma 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009162.3 Chromosome 19 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    endothelin-converting enzyme 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009162.3 Reference EquCab3.0 Primary Assembly

      Range
      24941740..24971770
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023623421.1 → XP_023479189.1  endothelin-converting enzyme 2 isoform X9

      Conserved Domains (1) summary
      pfam13649
      Location:62 → 169
      Methyltransf_25; Methyltransferase domain

    2. XM_023623422.1 → XP_023479190.1  endothelin-converting enzyme 2 isoform X10

      UniProtKB/TrEMBL
      A0A9L0S4Q3
      Related
      ENSECAP00000069034.1, ENSECAT00000125284.1
      Conserved Domains (2) summary
      cd08662
      Location:262 → 910
      M13; Peptidase family M13 includes neprilysin, endothelin-converting enzyme I
      pfam13649
      Location:62 → 128
      Methyltransf_25; Methyltransferase domain

    3. XM_023623418.1 → XP_023479186.1  endothelin-converting enzyme 2 isoform X2

      Conserved Domains (1) summary
      cd08662
      Location:148 → 741
      M13; Peptidase family M13 includes neprilysin, endothelin-converting enzyme I

    4. XM_001497604.5 → XP_001497654.1  endothelin-converting enzyme 2 isoform X3

      UniProtKB/TrEMBL
      A0A5F5PSC6
      Conserved Domains (2) summary
      cd08662
      Location:161 → 809
      M13; Peptidase family M13 includes neprilysin, endothelin-converting enzyme I
      COG3590
      Location:149 → 802
      PepO; Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]

    5. XM_001497647.6 → XP_001497697.2  endothelin-converting enzyme 2 isoform X7

      UniProtKB/TrEMBL
      A0A9L0S4Q3
      Conserved Domains (2) summary
      cd08662
      Location:115 → 763
      M13; Peptidase family M13 includes neprilysin, endothelin-converting enzyme I
      COG3590
      Location:103 → 756
      PepO; Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]

    6. XM_014732778.2 → XP_014588264.1  endothelin-converting enzyme 2 isoform X1

      Conserved Domains (2) summary
      cd08662
      Location:161 → 754
      M13; Peptidase family M13 includes neprilysin, endothelin-converting enzyme I
      COG3590
      Location:149 → 770
      PepO; Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]

    7. XM_014732779.2 → XP_014588265.1  endothelin-converting enzyme 2 isoform X4

      Conserved Domains (2) summary
      cd08662
      Location:161 → 717
      M13; Peptidase family M13 includes neprilysin, endothelin-converting enzyme I
      COG3590
      Location:149 → 733
      PepO; Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]

    8. XM_005601848.3 → XP_005601905.1  endothelin-converting enzyme 2 isoform X5

      Conserved Domains (2) summary
      cd08662
      Location:115 → 708
      M13; Peptidase family M13 includes neprilysin, endothelin-converting enzyme I
      COG3590
      Location:103 → 724
      PepO; Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]

    9. XM_023623419.1 → XP_023479187.1  endothelin-converting enzyme 2 isoform X6

      Conserved Domains (1) summary
      cd08662
      Location:86 → 679
      M13; Peptidase family M13 includes neprilysin, endothelin-converting enzyme I

    10. XM_023623420.1 → XP_023479188.1  endothelin-converting enzyme 2 isoform X8

      UniProtKB/TrEMBL
      A0A5F5PSC6, A0A5F5PV43
      Related
      ENSECAP00000052117.2, ENSECAT00000072800.2
      Conserved Domains (1) summary
      cd08662
      Location:86 → 734
      M13; Peptidase family M13 includes neprilysin, endothelin-converting enzyme I
    Nucleotide Protein
    Heading Accession and Version

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