STAU1 staufen double-stranded RNA binding protein 1 [Equus caballus (horse)] - Gene

Summary

Official Symbol: STAU1provided by VGNC
Official Full Name: staufen double-stranded RNA binding protein 1provided by VGNC
Primary source: VGNC:VGNC:23669
See related: Ensembl:ENSECAG00000012894
Gene type: protein coding
RefSeq status: MODEL
Organism: Equus caballus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	EquCab3.0 (GCF_002863925.1)	22	NC_009165.3 (38319302..38373921, complement)

Chromosome 22 - NC_009165.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_009165.3 Chromosome 22 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables double-stranded RNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables mRNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in anterograde dendritic transport of messenger ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info	PubMed
involved_in germ cell development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular mRNA localization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein localization to synapse	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasmic stress granule	IEA Inferred from Electronic Annotation more info	PubMed
located_in neuron projection	IEA Inferred from Electronic Annotation more info	PubMed
located_in neuronal cell body	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: double-stranded RNA-binding protein Staufen homolog 1

Names: staufen, RNA binding protein, homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

NC_009165.3 Reference EquCab3.0 Primary Assembly

Range

38319302..38373921 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_023626705.1 → XP_023482473.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X5

UniProtKB/TrEMBL

A0A3Q2H0S1

Conserved Domains (3) summary

smart00358
Location:81 → 143

DSRM; Double-stranded RNA binding motif

pfam00035
Location:358 → 420

dsrm; Double-stranded RNA binding motif

pfam16482
Location:516 → 625

Staufen_C; Staufen C-terminal domain
XM_023626703.1 → XP_023482471.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X3

UniProtKB/TrEMBL

A0A3Q2H0S1

Conserved Domains (3) summary

smart00358
Location:81 → 143

DSRM; Double-stranded RNA binding motif

cd00048
Location:386 → 452

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:548 → 657

Staufen_C; Staufen C-terminal domain
XM_023626701.1 → XP_023482469.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X1

UniProtKB/TrEMBL

A0A3Q2H0S1

Conserved Domains (3) summary

smart00358
Location:81 → 143

DSRM; Double-stranded RNA binding motif

cd00048
Location:402 → 468

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:564 → 673

Staufen_C; Staufen C-terminal domain
XM_023626704.1 → XP_023482472.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X4

UniProtKB/TrEMBL

A0A3Q2H0S1

Related

ENSECAP00000026999.1, ENSECAT00000044803.3

Conserved Domains (3) summary

smart00358
Location:280 → 344

DSRM; Double-stranded RNA binding motif

cd00048
Location:380 → 446

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:542 → 651

Staufen_C; Staufen C-terminal domain
XM_023626702.1 → XP_023482470.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X2

UniProtKB/TrEMBL

A0A3Q2H0S1, A0A3Q2IAF6

Related

ENSECAP00000034828.2, ENSECAT00000042276.2

Conserved Domains (3) summary

smart00358
Location:296 → 360

DSRM; Double-stranded RNA binding motif

cd00048
Location:396 → 462

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:558 → 667

Staufen_C; Staufen C-terminal domain
XM_023626706.1 → XP_023482474.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X6

UniProtKB/TrEMBL

A0A3Q2L5V2

Conserved Domains (3) summary

smart00358
Location:186 → 256

DSRM; Double-stranded RNA binding motif

cd00048
Location:292 → 358

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:454 → 563

Staufen_C; Staufen C-terminal domain
XM_023626707.1 → XP_023482475.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X7

UniProtKB/TrEMBL

A0A3Q2L5V2, F7BJQ7

Related

ENSECAP00000011108.2, ENSECAT00000013949.3

Conserved Domains (3) summary

smart00358
Location:186 → 250

DSRM; Double-stranded RNA binding motif

cd00048
Location:286 → 352

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:448 → 557

Staufen_C; Staufen C-terminal domain
XM_023626711.1 → XP_023482479.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X8

UniProtKB/TrEMBL

A0A3Q2HQG6, A0A3Q2L5V2

Conserved Domains (3) summary

smart00358
Location:105 → 175

DSRM; Double-stranded RNA binding motif

cd00048
Location:211 → 277

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:373 → 482

Staufen_C; Staufen C-terminal domain
XM_023626708.1 → XP_023482476.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X8

UniProtKB/TrEMBL

A0A3Q2HQG6, A0A3Q2L5V2

Related

ENSECAP00000037169.2, ENSECAT00000057556.3

Conserved Domains (3) summary

smart00358
Location:105 → 175

DSRM; Double-stranded RNA binding motif

cd00048
Location:211 → 277

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:373 → 482

Staufen_C; Staufen C-terminal domain
XM_023626713.1 → XP_023482481.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X9

UniProtKB/TrEMBL

A0A3Q2L5V2

Related

ENSECAP00000033890.2, ENSECAT00000041645.2

Conserved Domains (3) summary

smart00358
Location:105 → 169

DSRM; Double-stranded RNA binding motif

cd00048
Location:205 → 271

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:367 → 476

Staufen_C; Staufen C-terminal domain
XM_023626709.1 → XP_023482477.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X8

UniProtKB/TrEMBL

A0A3Q2HQG6, A0A3Q2L5V2

Conserved Domains (3) summary

smart00358
Location:105 → 175

DSRM; Double-stranded RNA binding motif

cd00048
Location:211 → 277

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:373 → 482

Staufen_C; Staufen C-terminal domain
XM_023626712.1 → XP_023482480.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X8

UniProtKB/TrEMBL

A0A3Q2HQG6, A0A3Q2L5V2

Conserved Domains (3) summary

smart00358
Location:105 → 175

DSRM; Double-stranded RNA binding motif

cd00048
Location:211 → 277

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:373 → 482

Staufen_C; Staufen C-terminal domain
XM_023626710.1 → XP_023482478.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X8

UniProtKB/TrEMBL

A0A3Q2HQG6, A0A3Q2L5V2

Conserved Domains (3) summary

smart00358
Location:105 → 175

DSRM; Double-stranded RNA binding motif

cd00048
Location:211 → 277

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:373 → 482

Staufen_C; Staufen C-terminal domain
XM_023626714.1 → XP_023482482.1 double-stranded RNA-binding protein Staufen homolog 1 isoform X10

Conserved Domains (3) summary

smart00358
Location:280 → 344

DSRM; Double-stranded RNA binding motif

cd00048
Location:380 → 446

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam16482
Location:542 → 651

Staufen_C; Staufen C-terminal domain