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    MYLK3 myosin light chain kinase 3 [ Equus caballus (horse) ]

    Gene ID: 100056559, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MYLK3provided by VGNC
    Official Full Name
    myosin light chain kinase 3provided by VGNC
    Primary source
    VGNC:VGNC:20490
    See related
    Ensembl:ENSECAG00000008775
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See MYLK3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 3 NC_009146.3 (158175..215236, complement)

    Chromosome 3 - NC_009146.3Genomic Context describing neighboring genes Neighboring gene SHC binding and spindle associated 1 Neighboring gene VPS35 retromer complex component Neighboring gene uncharacterized LOC111773035 Neighboring gene origin recognition complex subunit 6 Neighboring gene ras-related protein Rap-1A Neighboring gene chromosome 3 C16orf87 homolog Neighboring gene uncharacterized LOC111772733

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009146.3 Chromosome 3 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myosin light chain kinase 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009146.3 Reference EquCab3.0 Primary Assembly

      Range
      158175..215236 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014738321.2 → XP_014593807.1  myosin light chain kinase 3 isoform X4

      Conserved Domains (2) summary
      smart00220
      Location:355 → 607
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14192
      Location:347 → 607
      STKc_MLCK3; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 3

    2. XM_023636894.1 → XP_023492662.1  myosin light chain kinase 3 isoform X5

      UniProtKB/TrEMBL
      A0A9L0SK69
      Related
      ENSECAP00000074604.1, ENSECAT00000147795.1
      Conserved Domains (1) summary
      cd14192
      Location:289 → 549
      STKc_MLCK3; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 3

    3. XM_014738322.2 → XP_014593808.1  myosin light chain kinase 3 isoform X5

      UniProtKB/TrEMBL
      A0A9L0SK69
      Conserved Domains (1) summary
      cd14192
      Location:289 → 549
      STKc_MLCK3; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 3

    4. XM_014738318.2 → XP_014593804.1  myosin light chain kinase 3 isoform X3

      Conserved Domains (2) summary
      smart00220
      Location:378 → 630
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14192
      Location:370 → 630
      STKc_MLCK3; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 3

    5. XM_014738323.2 → XP_014593809.1  myosin light chain kinase 3 isoform X5

      UniProtKB/TrEMBL
      A0A9L0SK69
      Conserved Domains (1) summary
      cd14192
      Location:289 → 549
      STKc_MLCK3; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 3

    6. XM_001490251.4 → XP_001490301.1  myosin light chain kinase 3 isoform X1

      UniProtKB/TrEMBL
      F6QXX1
      Related
      ENSECAP00000006853.2, ENSECAT00000009065.3
      Conserved Domains (2) summary
      smart00220
      Location:508 → 760
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14192
      Location:500 → 760
      STKc_MLCK3; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 3

    7. XM_014738317.2 → XP_014593803.1  myosin light chain kinase 3 isoform X2

      Conserved Domains (2) summary
      smart00220
      Location:392 → 644
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14192
      Location:384 → 644
      STKc_MLCK3; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 3
    Nucleotide Protein
    Heading Accession and Version

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