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    UBR1 ubiquitin protein ligase E3 component n-recognin 1 [ Equus caballus (horse) ]

    Gene ID: 100056497, updated on 17-Aug-2024

    Summary

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    Official Symbol
    UBR1provided by VGNC
    Official Full Name
    ubiquitin protein ligase E3 component n-recognin 1provided by VGNC
    Primary source
    VGNC:VGNC:24747
    See related
    Ensembl:ENSECAG00000011972
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See UBR1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    48
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 1 NC_009144.3 (147291737..147457679)

    Chromosome 1 - NC_009144.3Genomic Context describing neighboring genes Neighboring gene cyclin D1 binding protein 1 Neighboring gene transmembrane protein 62 Neighboring gene uncharacterized LOC111768093 Neighboring gene small nucleolar RNA SNORD50 Neighboring gene tau tubulin kinase 2 Neighboring gene elongation factor 1-alpha 1 pseudogene Neighboring gene codanin 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009144.3 Chromosome 1 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process via the N-end rule pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase UBR1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009144.3 Reference EquCab3.0 Primary Assembly

      Range
      147291737..147457679
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023618975.1 → XP_023474743.1  E3 ubiquitin-protein ligase UBR1 isoform X1

      UniProtKB/TrEMBL
      A0A9L0SWT7
      Related
      ENSECAP00000077509.1, ENSECAT00000123268.1
      Conserved Domains (3) summary
      pfam02207
      Location:99 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:221 → 301
      ClpS; ATP-dependent Clp protease adaptor protein ClpS
      cl17238
      Location:1097 → 1215
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    2. XM_023618985.1 → XP_023474753.1  E3 ubiquitin-protein ligase UBR1 isoform X3

      UniProtKB/TrEMBL
      F6SW37
      Conserved Domains (3) summary
      pfam02207
      Location:99 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:221 → 301
      ClpS; ATP-dependent Clp protease adaptor protein ClpS
      cd16685
      Location:1097 → 1215
      RING-H2_UBR1; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-1 (UBR1) and similar proteins

    3. XM_005603097.3 → XP_005603154.1  E3 ubiquitin-protein ligase UBR1 isoform X2

      UniProtKB/TrEMBL
      A0A9L0SDN1
      Related
      ENSECAP00000074221.1, ENSECAT00000121497.1
      Conserved Domains (2) summary
      pfam02207
      Location:1 → 27
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:82 → 162
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    RNA

    1. XR_001379023.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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