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    MIER1 MIER1 transcriptional regulator [ Equus caballus (horse) ]

    Gene ID: 100053862, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MIER1provided by VGNC
    Official Full Name
    MIER1 transcriptional regulatorprovided by VGNC
    Primary source
    VGNC:VGNC:20181
    See related
    Ensembl:ENSECAG00000020475
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See MIER1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 5 NC_009148.3 (91060666..91119399, complement)

    Chromosome 5 - NC_009148.3Genomic Context describing neighboring genes Neighboring gene chromosome 5 C1orf141 homolog Neighboring gene microRNA mir-8971 Neighboring gene dynein axonemal intermediate chain 4 Neighboring gene insulin like 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009148.3 Chromosome 5 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone deacetylase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mesoderm induction early response protein 1
    Names
    mesoderm induction early response 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009148.3 Reference EquCab3.0 Primary Assembly

      Range
      91060666..91119399 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001500074.6 → XP_001500124.1  mesoderm induction early response protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2KPF6
      Related
      ENSECAP00000088913.1, ENSECAT00000134609.1
      Conserved Domains (3) summary
      smart00717
      Location:340 → 385
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11661
      Location:340 → 384
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:234 → 283
      ELM2; ELM2 domain

    2. XM_005610513.3 → XP_005610570.1  mesoderm induction early response protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q2KPF6
      Conserved Domains (3) summary
      smart00717
      Location:354 → 399
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11661
      Location:354 → 398
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:248 → 297
      ELM2; ELM2 domain

    3. XM_023641915.1 → XP_023497683.1  mesoderm induction early response protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A3Q2KPF6
      Conserved Domains (2) summary
      cd11661
      Location:287 → 331
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:181 → 230
      ELM2; ELM2 domain

    4. XM_023641913.1 → XP_023497681.1  mesoderm induction early response protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A5F5PTN1, A0A9L0SDI7
      Conserved Domains (2) summary
      cd11661
      Location:305 → 349
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:199 → 248
      ELM2; ELM2 domain

    5. XM_005610515.3 → XP_005610572.1  mesoderm induction early response protein 1 isoform X3

      See identical proteins and their annotated locations for XP_005610572.1

      UniProtKB/TrEMBL
      A0A5F5PTN1, A0A9L0SDI7
      Related
      ENSECAP00000072234.1, ENSECAT00000093560.1
      Conserved Domains (2) summary
      cd11661
      Location:305 → 349
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:199 → 248
      ELM2; ELM2 domain

    6. XM_023641914.1 → XP_023497682.1  mesoderm induction early response protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A3Q2KPF6
      Related
      ENSECAP00000025120.2, ENSECAT00000051671.2
      Conserved Domains (2) summary
      cd11661
      Location:288 → 332
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:182 → 231
      ELM2; ELM2 domain
    Nucleotide Protein
    Heading Accession and Version

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