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    AGXT2 alanine--glyoxylate aminotransferase 2 [ Equus caballus (horse) ]

    Gene ID: 100053849, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AGXT2provided by VGNC
    Official Full Name
    alanine--glyoxylate aminotransferase 2provided by VGNC
    Primary source
    VGNC:VGNC:59164
    See related
    Ensembl:ENSECAG00000021933
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See AGXT2 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 21 NC_009164.3 (31108511..31145285)

    Chromosome 21 - NC_009164.3Genomic Context describing neighboring genes Neighboring gene sperm flagellar 2 Neighboring gene prolactin receptor Neighboring gene uncharacterized LOC106782348 Neighboring gene DnaJ heat shock protein family (Hsp40) member C21 Neighboring gene biogenesis of ribosomes BRX1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009164.3 Chromosome 21 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alanine-glyoxylate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-alanine catabolic process, by transamination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glyoxylate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alanine--glyoxylate aminotransferase 2, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009164.3 Reference EquCab3.0 Primary Assembly

      Range
      31108511..31145285
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014734911.2 → XP_014590397.1  alanine--glyoxylate aminotransferase 2, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A5F5Q1S1
      Conserved Domains (2) summary
      cd00610
      Location:66 → 429
      OAT_like; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, ...
      COG0160
      Location:53 → 429
      GabT; 4-aminobutyrate aminotransferase or related aminotransferase [Amino acid transport and metabolism]

    2. XM_001500116.5 → XP_001500166.2  alanine--glyoxylate aminotransferase 2, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A5F5Q1S1
      Related
      ENSECAP00000019476.4, ENSECAT00000023509.4
      Conserved Domains (2) summary
      cd00610
      Location:66 → 504
      OAT_like; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, ...
      COG0160
      Location:53 → 504
      GabT; 4-aminobutyrate aminotransferase or related aminotransferase [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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