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    CTCF CCCTC-binding factor [ Equus caballus (horse) ]

    Gene ID: 100053363, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CTCFprovided by VGNC
    Official Full Name
    CCCTC-binding factorprovided by VGNC
    Primary source
    VGNC:VGNC:16928
    See related
    Ensembl:ENSECAG00000015924
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See CTCF in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 3 NC_009146.3 (18666243..18715665)

    Chromosome 3 - NC_009146.3Genomic Context describing neighboring genes Neighboring gene RHO family interacting cell polarization regulator 1 Neighboring gene agouti related neuropeptide Neighboring gene uncharacterized LOC111773014 Neighboring gene uncharacterized LOC111773013 Neighboring gene uncharacterized LOC111773015 Neighboring gene capping protein regulator and myosin 1 linker 2 Neighboring gene par-6 family cell polarity regulator alpha Neighboring gene ACD shelterin complex subunit and telomerase recruitment factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009146.3 Chromosome 3 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcriptional repressor CTCF

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009146.3 Reference EquCab3.0 Primary Assembly

      Range
      18666243..18715665
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023638657.1 → XP_023494425.1  transcriptional repressor CTCF isoform X1

      UniProtKB/TrEMBL
      A0A9L0SJ79
      Related
      ENSECAP00000074244.1, ENSECAT00000139808.1
      Conserved Domains (3) summary
      COG5048
      Location:366 → 500
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:268 → 288
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:509 → 534
      zf-H2C2_2; Zinc-finger double domain

    2. XM_023638658.1 → XP_023494426.1  transcriptional repressor CTCF isoform X2

      UniProtKB/TrEMBL
      A0A9L0SJ79
      Related
      ENSECAP00000013721.4, ENSECAT00000016951.4
      Conserved Domains (3) summary
      COG5048
      Location:366 → 500
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:268 → 288
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:509 → 534
      zf-H2C2_2; Zinc-finger double domain

    3. XM_023638659.1 → XP_023494427.1  transcriptional repressor CTCF isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:38 → 172
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:25 → 45
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:181 → 206
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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