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    NR1H2 nuclear receptor subfamily 1 group H member 2 [ Equus caballus (horse) ]

    Gene ID: 100052399, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NR1H2provided by VGNC
    Official Full Name
    nuclear receptor subfamily 1 group H member 2provided by VGNC
    Primary source
    VGNC:VGNC:20860
    See related
    Ensembl:ENSECAG00000020882
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See NR1H2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 10 NC_009153.3 (20206202..20212446)

    Chromosome 10 - NC_009153.3Genomic Context describing neighboring genes Neighboring gene napsin A aspartic peptidase Neighboring gene serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform pseudogene Neighboring gene DNA polymerase delta 1, catalytic subunit Neighboring gene Spi-B transcription factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009153.3 Chromosome 10 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    oxysterols receptor LXR-beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009153.3 Reference EquCab3.0 Primary Assembly

      Range
      20206202..20212446
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001493800.4 → XP_001493850.1  oxysterols receptor LXR-beta

      See identical proteins and their annotated locations for XP_001493850.1

      UniProtKB/TrEMBL
      A0A3Q2HVS6, F6TR06
      Related
      ENSECAP00000018458.1, ENSECAT00000022344.4
      Conserved Domains (2) summary
      cd06954
      Location:220 → 455
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    Nucleotide Protein
    Heading Accession and Version

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