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    NPFFR2 neuropeptide FF receptor 2 [ Equus caballus (horse) ]

    Gene ID: 100050041, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NPFFR2provided by VGNC
    Official Full Name
    neuropeptide FF receptor 2provided by VGNC
    Primary source
    VGNC:VGNC:20835
    See related
    Ensembl:ENSECAG00000006685
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See NPFFR2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 3 NC_009146.3 (64997357..65041770, complement)

    Chromosome 3 - NC_009146.3Genomic Context describing neighboring genes Neighboring gene A disintegrin and metalloproteinase with thrombospondin motifs 3 Neighboring gene A disintegrin and metalloproteinase with thrombospondin motifs 3 Neighboring gene GC vitamin D binding protein Neighboring gene solute carrier family 4 member 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009146.3 Chromosome 3 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables neuropeptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables opioid receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peptide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to hormone stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of adenylate cyclase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cAMP-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuropeptide FF receptor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009146.3 Reference EquCab3.0 Primary Assembly

      Range
      64997357..65041770 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005608726.3 → XP_005608783.2  neuropeptide FF receptor 2

      UniProtKB/TrEMBL
      F6U1B7
      Conserved Domains (2) summary
      cd15980
      Location:45 → 69
      7tmA_NPFFR2; TM helix 1 [structural motif]
      cl28897
      Location:43 → 341
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_023637988.1 → XP_023493756.1  neuropeptide FF receptor 2

      UniProtKB/TrEMBL
      F6U1B7
      Related
      ENSECAP00000004910.4, ENSECAT00000006835.4
      Conserved Domains (2) summary
      cd15980
      Location:45 → 69
      7tmA_NPFFR2; TM helix 1 [structural motif]
      cl28897
      Location:43 → 341
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version

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