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    NKX2-2 NK2 homeobox 2 [ Equus caballus (horse) ]

    Gene ID: 100050029, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NKX2-2provided by VGNC
    Official Full Name
    NK2 homeobox 2provided by VGNC
    Primary source
    VGNC:VGNC:20754
    See related
    Ensembl:ENSECAG00000018977
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See NKX2-2 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 22 NC_009165.3 (3802508..3805579)

    Chromosome 22 - NC_009165.3Genomic Context describing neighboring genes Neighboring gene forkhead box A2 Neighboring gene paired box 1 Neighboring gene NK2 homeobox 4 Neighboring gene 5'-3' exoribonuclease 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009165.3 Chromosome 22 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeobox protein Nkx-2.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009165.3 Reference EquCab3.0 Primary Assembly

      Range
      3802508..3805579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001489173.4 → XP_001489223.1  homeobox protein Nkx-2.2

      UniProtKB/TrEMBL
      F7A4A4
      Related
      ENSECAP00000016451.1, ENSECAT00000020059.4
      Conserved Domains (1) summary
      pfam00046
      Location:131 → 185
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version

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