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    adat2 adenosine deaminase tRNA specific 2 [ Danio rerio (zebrafish) ]

    Gene ID: 100034610, updated on 2-Nov-2024

    Summary

    Official Symbol
    adat2provided by ZNC
    Official Full Name
    adenosine deaminase tRNA specific 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041014-360
    See related
    Ensembl:ENSDARG00000041944 AllianceGenome:ZFIN:ZDB-GENE-041014-360
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    deadc1; si:ch211-157l15.2
    Summary
    Predicted to enable tRNA-specific adenosine-34 deaminase activity. Predicted to be involved in tRNA wobble adenosine to inosine editing. Predicted to act upstream of or within tRNA processing. Orthologous to human ADAT2 (adenosine deaminase tRNA specific 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See adat2 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (37681400..37760476, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (37830874..37857597, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene si:ch211-202p1.5 Neighboring gene androgen-induced 1 (H. sapiens) Neighboring gene HIVEP zinc finger 2a Neighboring gene peroxisomal biogenesis factor 3 Neighboring gene activating transcription factor 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables tRNA-specific adenosine deaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables tRNA-specific adenosine-34 deaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables tRNA-specific adenosine-34 deaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA wobble adenosine to inosine editing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within tRNA wobble adenosine to inosine editing IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    tRNA-specific adenosine deaminase 2
    Names
    adenosine deaminase, tRNA-specific 2, TAD2 homolog
    deaminase domain containing 1
    deaminase domain-containing protein 1
    tRNA-specific adenosine-34 deaminase subunit ADAT2
    NP_001076566.1
    XP_005160675.1
    XP_068071466.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083097.1NP_001076566.1  tRNA-specific adenosine deaminase 2

      See identical proteins and their annotated locations for NP_001076566.1

      Status: PROVISIONAL

      Source sequence(s)
      BX088644
      UniProtKB/TrEMBL
      B3DKA9
      Related
      ENSDARP00000103292.3, ENSDART00000115221.6
      Conserved Domains (1) summary
      COG0590
      Location:23172
      TadA; tRNA(Arg) A34 adenosine deaminase TadA [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      37681400..37760476 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068215365.1XP_068071466.1  tRNA-specific adenosine deaminase 2 isoform X2

    2. XM_005160618.5XP_005160675.1  tRNA-specific adenosine deaminase 2 isoform X1

      See identical proteins and their annotated locations for XP_005160675.1

      UniProtKB/Swiss-Prot
      A4IGI0, Q5RIV4
      Related
      ENSDARP00000127393.1, ENSDART00000152885.2
      Conserved Domains (1) summary
      COG0590
      Location:23172
      TadA; tRNA(Arg) A34 adenosine deaminase TadA [Translation, ribosomal structure and biogenesis]