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    GAPDH glyceraldehyde-3-phosphate dehydrogenase [ Equus caballus (horse) ]

    Gene ID: 100033897, updated on 15-Aug-2024

    Summary

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    Gene symbol
    GAPDH
    Gene description
    glyceraldehyde-3-phosphate dehydrogenase
    See related
    Ensembl:ENSECAG00000022051
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Also known as
    G3PDH
    Orthologs
    human mouse all
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    Genomic context

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    See GAPDH in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 6 NC_009149.3 (35091754..35096110)

    Chromosome 6 - NC_009149.3Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L51 Neighboring gene non-SMC condensin I complex subunit D2 Neighboring gene small nucleolar RNA U85 Neighboring gene intermediate filament family orphan 1 Neighboring gene NOP2 nucleolar protein Neighboring gene chromodomain helicase DNA binding protein 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009149.3 Chromosome 6 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression and regulation of transcripts encoding two members of the NR5A nuclear receptor subfamily of orphan nuclear receptors, steroidogenic factor-1 and NR5A2, in equine ovarian cells during the ovulatory process. Boerboom D, et al. Endocrinology, 2000 Dec. PMID 11108279
    2. Oxytocin-neurophysin I mRNA abundance in equine uterine endometrium. Behrendt-Adam CY, et al. Domest Anim Endocrinol, 1999 Apr. PMID 10343920
    3. Housekeeping genes for phylogenetic analysis of eutherian relationships. Kullberg M, et al. Mol Biol Evol, 2006 Aug. PMID 16751257
    4. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glyceraldehyde-3-phosphate dehydrogenase
    NP_001157328.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163856.1 → NP_001157328.1  glyceraldehyde-3-phosphate dehydrogenase

      Status: VALIDATED

      Source sequence(s)
      AF157626, BI960908, CX593628
      UniProtKB/TrEMBL
      F6Y457
      Related
      ENSECAP00000071805.1, ENSECAT00000098871.1
      Conserved Domains (3) summary
      COG0057
      Location:1 → 333
      GapA; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]
      pfam00044
      Location:2 → 150
      Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
      pfam02800
      Location:155 → 312
      Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain

    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009149.3 Reference EquCab3.0 Primary Assembly

      Range
      35091754..35096110
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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