SLC13A2 solute carrier family 13 member 2 [Oryctolagus cuniculus (rabbit)] - Gene

Summary

Gene symbol: SLC13A2
Gene description: solute carrier family 13 member 2
See related: Ensembl:ENSOCUG00000013757
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Oryctolagus cuniculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as: INDY; NADC1; SDCT1; NaDC-1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2023_02	current	UM_NZW_1.0 (GCF_009806435.1)	19	NC_067392.1 (17231640..17252661, complement)

Chromosome 19 - NC_067392.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_067392.1 Chromosome 19 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Mapping Functionally Important Residues in the Na(+)/Dicarboxylate Cotransporter, NaDC1.
Title: Mapping Functionally Important Residues in the Na(+)/Dicarboxylate Cotransporter, NaDC1.
Data show that NaDC1 F336C had increased transport activity due to an increased Vmax for succinate.
Title: Transmembrane helix 7 in the Na+/dicarboxylate cotransporter 1 is an outer helix that contains residues critical for function.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in monoatomic anion transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: solute carrier family 13 member 2

Names: Na(+)/dicarboxylate cotransporter 1; renal sodium/dicarboxylate cotransporter; sodium/dicarboxylate cotransporter; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001177592.2 → NP_001171063.1 solute carrier family 13 member 2

See identical proteins and their annotated locations for NP_001171063.1

Status: PROVISIONAL

Source sequence(s)

VIYN02003008

UniProtKB/Swiss-Prot

Q28615

UniProtKB/TrEMBL

A0A0A0MQQ0

Related

ENSOCUP00000011839.3, ENSOCUT00000013760.4

Conserved Domains (2) summary

TIGR00785
Location:43 → 561

dass; anion transporter

cl21473
Location:6 → 568

ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...