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    PPP3CA protein phosphatase 3 catalytic subunit alpha [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100009423, updated on 8-Mar-2024

    Summary

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    Gene symbol
    PPP3CA
    Gene description
    protein phosphatase 3 catalytic subunit alpha
    See related
    Ensembl:ENSOCUG00000011398
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See PPP3CA in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 15 NC_067388.1 (45435825..45763095)

    Chromosome 15 - NC_067388.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103350742 Neighboring gene transmembrane protein 216-like Neighboring gene leucine-rich repeat-containing protein 40-like Neighboring gene endomucin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067388.1 Chromosome 15 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning, expression, and function of osteoclastic calcineurin Aalpha. Sun L, et al. Am J Physiol Renal Physiol, 2003 Mar. PMID 12419772

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin-dependent protein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcineurin-NFAT signaling cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of calcineurin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase 3 catalytic subunit alpha
    Names
    calcineurin A alpha
    protein phosphatase 3, catalytic subunit, alpha isozyme
    protein phosphatase 3, catalytic subunit, gamma isozyme
    NP_001076161.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082692.1 → NP_001076161.1  protein phosphatase 3 catalytic subunit alpha

      See identical proteins and their annotated locations for NP_001076161.1

      Status: PROVISIONAL

      Source sequence(s)
      AF541960
      UniProtKB/TrEMBL
      G1U9T2, Q8HZN0
      Related
      ENSOCUP00000022899.1, ENSOCUT00000031231.3
      Conserved Domains (2) summary
      smart00156
      Location:58 → 329
      PP2Ac; Protein phosphatase 2A homologues, catalytic domain
      cd07416
      Location:41 → 345
      MPP_PP2B; PP2B, metallophosphatase domain

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067388.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      45435825..45763095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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