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    ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100009307, updated on 18-Sep-2024

    Summary

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    Gene symbol
    ADH5
    Gene description
    alcohol dehydrogenase 5 (class III), chi polypeptide
    See related
    Ensembl:ENSOCUG00000004263
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Also known as
    ADH3; ADH1C
    Annotation information
    Annotation category: partial on reference assembly
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    Genomic context

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    See ADH5 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 15 NC_067388.1 (47729696..47744600)

    Chromosome 15 - NC_067388.1Genomic Context describing neighboring genes Neighboring gene developmental pluripotency-associated protein 2-like Neighboring gene alcohol dehydrogenase class-2 isozyme 2 Neighboring gene methionyl aminopeptidase 1 Neighboring gene eukaryotic translation initiation factor 4E

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067388.1 Chromosome 15 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural and functional divergence of class II alcohol dehydrogenase--cloning and characterisation of rabbit liver isoforms of the enzyme. Svensson S, et al. Eur J Biochem, 1998 Jan 15. PMID 9492289
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in formaldehyde catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alcohol dehydrogenase class-3
    Names
    FALDH
    FDH
    GSH-FDH
    S-(hydroxymethyl)glutathione dehydrogenase
    alcohol dehydrogenase 1C (class I), gamma polypeptide
    alcohol dehydrogenase class-III
    class III alcohol dehydrogenase
    glutathione-dependent formaldehyde dehydrogenase
    NP_001076093.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082624.1 → NP_001076093.1  alcohol dehydrogenase class-3

      See identical proteins and their annotated locations for NP_001076093.1

      Status: PROVISIONAL

      Source sequence(s)
      Y15406
      UniProtKB/Swiss-Prot
      O19053
      UniProtKB/TrEMBL
      G1SLF1
      Related
      ENSOCUP00000003687.3, ENSOCUT00000004266.4
      Conserved Domains (2) summary
      cd08300
      Location:6 → 373
      alcohol_DH_class_III; class III alcohol dehydrogenases
      COG1062
      Location:6 → 374
      FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067388.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      47729696..47744600
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O19053.3 GenPept UniProtKB/Swiss-Prot:O19053

    Gene LinkOut

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