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    F9 coagulation factor IX [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100009113, updated on 8-Mar-2024

    Summary

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    Gene symbol
    F9
    Gene description
    coagulation factor IX
    See related
    Ensembl:ENSOCUG00000005240
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259152.1 (2754278..2787957)

    NW_026259152.1Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor 13 Neighboring gene serine/threonine/tyrosine-interacting protein-like Neighboring gene U6 spliceosomal RNA Neighboring gene MCF.2 cell line derived transforming sequence Neighboring gene ATPase phospholipid transporting 11C Neighboring gene microRNA mir-505

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_026259152 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Direct sequencing of the activation peptide and the catalytic domain of the factor IX gene in six species. Sarkar G, et al. Genomics, 1990 Jan. PMID 2303254

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in zymogen activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    coagulation factor IX
    Names
    christmas factor
    NP_001182654.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195725.2 → NP_001182654.1  coagulation factor IX

      Status: PROVISIONAL

      Source sequence(s)
      VIYN02003012
      UniProtKB/TrEMBL
      A0A5F9C3T7, G1U9U2
      Related
      ENSOCUP00000004537.2, ENSOCUT00000005236.4
      Conserved Domains (5) summary
      smart00020
      Location:227 → 455
      Tryp_SPc; Trypsin-like serine protease
      smart00069
      Location:28 → 92
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      cd00054
      Location:93 → 129
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00190
      Location:228 → 458
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam14670
      Location:134 → 170
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NW_026259152.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      2754278..2787957
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P16292.1 GenPept UniProtKB/Swiss-Prot:P16292

    Gene LinkOut

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