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    VCAM1 vascular cell adhesion molecule 1 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100008901, updated on 10-Oct-2024

    Summary

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    Gene symbol
    VCAM1
    Gene description
    vascular cell adhesion molecule 1
    See related
    Ensembl:ENSOCUG00000011697
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Also known as
    VCAM-1
    Orthologs
    human mouse all
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    Genomic context

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    See VCAM1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 13 NC_067386.1 (63660354..63681708, complement)

    Chromosome 13 - NC_067386.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 30 member 7 Neighboring gene KATNB1-like protein 1 Neighboring gene exostosin like glycosyltransferase 2 Neighboring gene uncharacterized LOC103350110 Neighboring gene G protein-coupled receptor 88

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067386.1 Chromosome 13 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Inhibition of basal and interleukin-1-induced VCAM-1 expression by phospholipid hydroperoxide glutathione peroxidase and 15-lipoxygenase in rabbit aortic smooth muscle cells. Banning A, et al. Free Radic Biol Med, 2004 Jan 15. PMID 14744625
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vascular cell adhesion protein 1
    Names
    adhesion molecule VCAM-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082152.1 → NP_001075621.1  vascular cell adhesion protein 1 precursor

      See identical proteins and their annotated locations for NP_001075621.1

      Status: PROVISIONAL

      Source sequence(s)
      AY212510
      UniProtKB/TrEMBL
      A0A5F9DFM7, Q865F2
      Related
      ENSOCUP00000044142.1, ENSOCUT00000059470.1
      Conserved Domains (7) summary
      cd07689
      Location:116 → 214
      Ig2_VCAM-1; Second immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1, CD106) and intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins
      smart00408
      Location:238 → 298
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:232 → 308
      IG_like; Immunoglobulin like
      pfam07679
      Location:26 → 112
      I-set; Immunoglobulin I-set domain
      pfam13895
      Location:518 → 596
      Ig_2; Immunoglobulin domain
      pfam13927
      Location:608 → 672
      Ig_3; Immunoglobulin domain
      cl11960
      Location:29 → 98
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067386.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      63660354..63681708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008263958.3 → XP_008262180.2  vascular cell adhesion protein 1 isoform X1

    2. XM_008263959.3 → XP_008262181.2  vascular cell adhesion protein 1 isoform X2

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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