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    kcnip2 Kv channel interacting protein 2 [ Danio rerio (zebrafish) ]

    Gene ID: 100003947, updated on 27-Mar-2024

    Summary

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    Official Symbol
    kcnip2provided by ZNC
    Official Full Name
    Kv channel interacting protein 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081031-91
    See related
    Ensembl:ENSDARG00000075846 AllianceGenome:ZFIN:ZDB-GENE-081031-91
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch73-173h19.2
    Summary
    Predicted to enable calcium ion binding activity. Orthologous to human KCNIP2 (potassium voltage-gated channel interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See kcnip2 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (34984959..35006772, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (35009500..35030858, complement)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene slit homolog 1b (Drosophila) Neighboring gene Rho GTPase activating protein 19 Neighboring gene armadillo like helical domain containing 3 Neighboring gene si:ch73-173h19.3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Kcnb1 plays a role in development of the inner ear. Jedrychowska J, et al. Dev Biol, 2021 Mar. PMID 33316259
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium channel regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of potassium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of voltage-gated potassium channel complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Kv channel-interacting protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      34984959..35006772 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003201139.5 → XP_003201187.1  Kv channel-interacting protein 2

      UniProtKB/TrEMBL
      A0A8M1RTI3
      Related
      ENSDARP00000123370.1, ENSDART00000138639.3
      Conserved Domains (2) summary
      COG5126
      Location:72 → 242
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      cd00051
      Location:163 → 234
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    Nucleotide Protein
    Heading Accession and Version

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