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    Ir84a Ionotropic receptor 84a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40891, updated on 11-Sep-2024

    Summary

    Official Symbol
    Ir84aprovided by FlyBase
    Official Full Name
    Ionotropic receptor 84aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037501
    Locus tag
    Dmel_CG10101
    See related
    AllianceGenome:FB:FBgn0037501
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    84a; CG10101; CT28433; DmelIR84a; Dmel\CG10101; IR84a
    Summary
    Enables co-receptor binding activity and extracellular phenylacetaldehyde-gated ion channel activity. Contributes to olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell; male courtship behavior; and transmission of nerve impulse. Located in dendrite terminus; neuronal cell body; and sensory dendrite. Is integral component of plasma membrane. Part of receptor complex. Is expressed in adult olfactory receptor neuron Ir84a; antennal coeloconic sensillum ac4; antennal lobe glomerulus VL2a; antennal sense organ; and coeloconic sensillum of antennal segment 3. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    84D6-84D6; 3-48 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (7406869..7409384)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (3232591..3235106)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45560 Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene walker cup

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in dendrite terminus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of receptor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in sensory dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ionotropic receptor 84a
    Names
    CG10101-PB
    Ir84a-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      7406869..7409384
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141463.2NP_649720.2  ionotropic receptor 84a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649720.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E9NA99, Q9VIA5
      Conserved Domains (3) summary
      pfam00060
      Location:355602
      Lig_chan; Ligand-gated ion channel
      cl00015
      Location:54112
      nt_trans; nucleotidyl transferase superfamily
      cl21456
      Location:222583
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily