U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    MIR4709 microRNA 4709 [ Homo sapiens (human) ]

    Gene ID: 100616211, updated on 12-Sep-2024

    Summary

    Official Symbol
    MIR4709provided by HGNC
    Official Full Name
    microRNA 4709provided by HGNC
    Primary source
    HGNC:HGNC:41690
    See related
    Ensembl:ENSG00000283944 miRBase:MI0017342; AllianceGenome:HGNC:41690
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    mir-4709
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    14q24.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (74480133..74480204, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (68689103..68689174, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (74946836..74946907, complement)

    Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene SUB1 pseudogene 2 Neighboring gene vertebrae development associated Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74792429-74793048 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74794289-74794910 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:74796151-74796770 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74815437-74816187 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74816188-74816937 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:74825115-74825693 Neighboring gene ribosomal protein S2 pseudogene 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:74861891-74862391 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74868255-74869164 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:74873841-74874342 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:74876293-74876840 Neighboring gene synapse differentiation inducing 1 like Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr14:74954493-74955692 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5930 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5931 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8728 Neighboring gene RAP1A, member of RAS oncogene family pseudogene Neighboring gene NPC intracellular cholesterol transporter 2 Neighboring gene iron-sulfur cluster assembly 2

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_039858.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AC005479
      Related
      ENST00000577272.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

      Range
      74480133..74480204 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060938.1 Alternate T2T-CHM13v2.0

      Range
      68689103..68689174 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)