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    abf-3 AntiBacterial Factor related [ Caenorhabditis elegans ]

    Gene ID: 186202, updated on 2-Nov-2024

    Summary

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    Official Symbol
    abf-3
    Official Full Name
    AntiBacterial Factor related
    Primary source
    WormBase:WBGene00000014
    Locus tag
    CELE_F54B8.5
    See related
    AllianceGenome:WB:WBGene00000014
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in defense response to Gram-negative bacterium and innate immune response. Is expressed in intestine and rectal gland cell. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See abf-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    2
    Sequence:
    Chromosome: V; NC_003283.11 (15817410..15817846, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene F-box domain-containing protein Neighboring gene Small, acid-soluble spore protein gamma-type Neighboring gene pseudo Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Immunological pathogenesis of Bovine E. coli infection in a model of C. elegans. Peng H, et al. BMC Microbiol, 2022 Dec 20. PMID 36539715, Free PMC Article
    2. Cell Signaling of Caenorhabditis elegans in Response to Enterotoxigenic Escherichia coli Infection and Lactobacillus zeae Protection. Zhou M, et al. Front Immunol, 2018. PMID 30250464, Free PMC Article
    3. Lactobacillus Regulates Caenorhabditis elegans Cell Signaling to Combat Salmonella Infection. Zhou M, et al. Front Immunol, 2021. PMID 33763087, Free PMC Article
    4. Specificity and complexity of the Caenorhabditis elegans innate immune response. Alper S, et al. Mol Cell Biol, 2007 Aug. PMID 17526726, Free PMC Article
    5. Caenorhabditis elegans: a model genetic host to study Pseudomonas aeruginosa pathogenesis. Tan MW, et al. Curr Opin Microbiol, 2000 Feb. PMID 10679415

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in innate immune response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    AntiBacterial Factor related
    NP_506950.1
    • Product from WormBase gene class abf;
      Predicted

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      15817410..15817846 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074549.1 → NP_506950.1  AntiBacterial Factor related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506950.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45563
    Nucleotide Protein
    Heading Accession and Version

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