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    uvrY putative LuxR/UhpA family response regulator [ Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 ]

    Gene ID: 1253468, updated on 4-Feb-2024

    Summary

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    Gene symbol
    uvrY
    Gene description
    putative LuxR/UhpA family response regulator
    Locus tag
    STM1947
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 (strain: LT2, serovar: Typhimurium, sub-species: enterica, culture-collection: ATCC:700720, culture-collection: SGSC:1412, type-material: type strain of Salmonella enterica)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella
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    Genomic context

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    Sequence:
    NC_003197.2 (2038244..2038914, complement)

    NC_003197.2Genomic Context describing neighboring genes Neighboring gene tRNA-Gly Neighboring gene phosphatidylglycerophosphate synthetase Neighboring gene UvrC Neighboring gene putative inner membrane protein Neighboring gene putative cytoplasmic protein Neighboring gene transcriptional regulator of ftsQAZ gene cluster

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003197.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Salmonella pathogenicity island 4-mediated adhesion is coregulated with invasion genes in Salmonella enterica. Gerlach RG, et al. Infect Immun, 2007 Oct. PMID 17635868, Free PMC Article
    2. Integration of a complex regulatory cascade involving the SirA/BarA and Csr global regulatory systems that controls expression of the Salmonella SPI-1 and SPI-2 virulence regulons through HilD. Martínez LC, et al. Mol Microbiol, 2011 Jun. PMID 21518393, Free PMC Article
    3. Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. McClelland M, et al. Nature, 2001 Oct 25. PMID 11677609

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SirA positively regulates expression of hilD and the SPI-1 and SPI-2 genes through activation of CsrB and CsrC expression.
      Title: Integration of a complex regulatory cascade involving the SirA/BarA and Csr global regulatory systems that controls expression of the Salmonella SPI-1 and SPI-2 virulence regulons through HilD.
    2. Both SirA and HilA functions were required for the secretion of SiiE and the SPI4-mediated adhesion.
      Title: Salmonella pathogenicity island 4-mediated adhesion is coregulated with invasion genes in Salmonella enterica.
    Submit: New GeneRIF Correction

    General gene information

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    regulatory

    • Loc: c2038267-2038262 regulatory_class = ribosome_binding_site
    • Loc: c2038914-2038909 regulatory_class = ribosome_binding_site

    General protein information

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    Preferred Names
    putative LuxR/UhpA family response regulator
    NP_460900.1
    • similar to E. coli putative 2-component transcriptional regulator (AAC74981.1); Blastp hit to AAC74981.1 (218 aa), 96% identity in aa 1 - 218

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003197.2 Reference assembly

      Range
      2038244..2038914 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_460900.1 putative LuxR/UhpA family response regulator [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]

      See identical proteins and their annotated locations for NP_460900.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X8WC15, A0A5T3RAL3, A0A5T6XNI6, A0A5T9SH54, A0A5T9W6L7, A0A5V5D2N8, A0A5Y0N0Q8, A0A5Y4VXV1, A0A5Z6ACU0, A0A605LZL1, A0A6X7RTF1, A0A6X8DYQ2, A0A711CKS9, A0A715TSY3, A0A726P814, A0A727TC56, A0A729NKJ0, A0A730QZ57, A0A732RBG0, A0A747M1J1, A0A750RJG4, A0A751UN11, A0A754QSI3, A0A757VW57, A0A7D8ITQ9
      Conserved Domains (1) summary
      PRK09483
      Location:1 → 218
      PRK09483; response regulator; Provisional
    Nucleotide Protein
    Heading Accession and Version

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