U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    SPDYE15 speedy/RINGO cell cycle regulator family member E15 [ Homo sapiens (human) ]

    Gene ID: 105180391, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SPDYE15provided by HGNC
    Official Full Name
    speedy/RINGO cell cycle regulator family member E15provided by HGNC
    Primary source
    HGNC:HGNC:51511
    See related
    Ensembl:ENSG00000286014 AllianceGenome:HGNC:51511
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SPDYE15P
    Summary
    Predicted to enable protein kinase binding activity. Predicted to be involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity. [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SPDYE15 in Genome Data Viewer
    Location:
    7q11.23
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (75335343..75347701)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (76538563..76548628)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (74964556..74974618)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene speedy/RINGO cell cycle regulator family member E14 Neighboring gene PMS1 homolog 2, mismatch repair system component pseudogene 13 Neighboring gene PMS1 homolog 2, mismatch repair system component pseudogene 10 Neighboring gene PMS1 homolog 2, mismatch repair system component pseudogene 2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:74987999-74988519 Neighboring gene uncharacterized LOC124901677 Neighboring gene STAG3 cohesin complex component like 1 (pseudogene) Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:75024300-75024907 Neighboring gene FKBP6 pseudogene 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

    Go to the top of the page Help

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    Genotypes

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    putative speedy protein E15
    Names
    Williams Beuren syndrome chromosome region 19 pseudogene
    speedy homolog E1 pseudogene
    speedy/RINGO cell cycle regulator family member E1 pseudogene
    speedy/RINGO cell cycle regulator family member E15, pseudogene

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001382547.2 → NP_001369476.1  putative speedy protein E15

      Status: VALIDATED

      Source sequence(s)
      AC211486
      Consensus CDS
      CCDS94127.1
      UniProtKB/Swiss-Prot
      A0A494C0Z2, P0DUD3, P0DUD4
      Related
      ENSP00000499200.1, ENST00000612377.3
      Conserved Domains (1) summary
      pfam11357
      Location:107 → 261
      Spy1; Cell cycle regulatory protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      75335343..75347701
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047419778.1 → XP_047275734.1  putative speedy protein E15 isoform X1

      UniProtKB/Swiss-Prot
      A0A494C0Z2, P0DUD3, P0DUD4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      76538563..76548628
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_041825.1: Suppressed sequence

      Description
      NG_041825.1: This RefSeq was removed because it is now thought that this locus is transcribed.

    2. NR_146074.1: Suppressed sequence

      Description
      NR_146074.1: This RefSeq was removed because it is now thought that this gene does encode a protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0DUD4.1 GenPept UniProtKB/Swiss-Prot:P0DUD4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials