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    RPN5B regulatory particle non-ATPase subunit 5B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836597, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPN5B
    Official Full Name
    regulatory particle non-ATPase subunit 5B
    Primary source
    TAIR:AT5G64760
    Locus tag
    AT5G64760
    See related
    Araport:AT5G64760
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MVP7.9; MVP7_9; regulatory particle non-ATPase subunit 5B
    Summary
    Encodes one of two isoforms for the 26S proteasome regulatory protein (RN) subunit RPN5. For many functions it acts redundantly with the paralogous genes RPN5a.
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    Genomic context

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    See RPN5B in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Sequence:
    Chromosome: 5; NC_003076.8 (25893780..25896586, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene cellulose synthase 6 Neighboring gene ncRNA Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene root meristem growth factor Neighboring gene holocarboxylase synthetase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The RPN5 subunit of the 26s proteasome is essential for gametogenesis, sporophyte development, and complex assembly in Arabidopsis. Book AJ, et al. Plant Cell, 2009 Feb. PMID 19252082, Free PMC Article
    2. Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome. Fu H, et al. EMBO J, 2001 Dec 17. PMID 11742986, Free PMC Article
    3. Structure and functional analysis of the 26S proteasome subunits from plants. Fu H, et al. Mol Biol Rep, 1999 Apr. PMID 10363660
    4. Affinity purification of the Arabidopsis 26 S proteasome reveals a diverse array of plant proteolytic complexes. Book AJ, et al. J Biol Chem, 2010 Aug 13. PMID 20516081, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The regulatory particle non-ATPase subunit (RPN5) encoded by RPN5a and RPN5b has a unique role in proteasome function and Arabidopsis development.
      Title: The RPN5 subunit of the 26s proteasome is essential for gametogenesis, sporophyte development, and complex assembly in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001037065.2
    NM_001345648.1
    NM_125872.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within multicellular organism development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 
    part_of proteasome complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    regulatory particle non-ATPase subunit 5B
    NP_001032142.1
    • regulatory particle non-ATPase subunit 5B (RPN5B); CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Proteasome component (PCI) domain (InterPro:IPR000717); BEST Arabidopsis thaliana protein match is: 26S proteasome regulatory subunit, putative (RPN5) (TAIR:AT5G09900.2); Has 838 Blast hits to 828 proteins in 229 species: Archae - 0; Bacteria - 0; Metazoa - 302; Fungi - 291; Plants - 115; Viruses - 0; Other Eukaryotes - 130 (source: NCBI BLink).
    NP_568994.2
    • regulatory particle non-ATPase subunit 5B (RPN5B); CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Proteasome component (PCI) domain (InterPro:IPR000717); BEST Arabidopsis thaliana protein match is: 26S proteasome regulatory subunit, putative (RPN5) (TAIR:AT5G09900.1); Has 840 Blast hits to 830 proteins in 229 species: Archae - 0; Bacteria - 0; Metazoa - 302; Fungi - 291; Plants - 115; Viruses - 0; Other Eukaryotes - 132 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25893780..25896586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125872.4 → NP_568994.2  regulatory particle non-ATPase subunit 5B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568994.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VWK0, Q9FGF7
      UniProtKB/TrEMBL
      A0A178UGS0
      Conserved Domains (1) summary
      COG5071
      Location:7 → 438
      RPN5; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]

    2. NM_001037065.2 → NP_001032142.1  regulatory particle non-ATPase subunit 5B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001032142.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UGS0, F4KF39
      Conserved Domains (1) summary
      COG5071
      Location:7 → 438
      RPN5; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]

    3. NM_001345648.1 → NP_001332553.1  regulatory particle non-ATPase subunit 5B [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UGS0, A0A1P8BHB1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VWK0.1

    Gene LinkOut

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