DOT4 Pentatricopeptide repeat (PPR) superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: DOT4
Official Full Name: Pentatricopeptide repeat (PPR) superfamily protein
Primary source: TAIR:AT4G18750
Locus tag: AT4G18750
See related: Araport:AT4G18750
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: DEFECTIVELY ORGANIZED TRIBUTARIES 4; F28A21.160; F28A21_160
Summary: Encodes a pentatricopeptide (PPR) protein involved in leaf and root development. dot4 mutants have an aberrant midgap venation pattern in juvenile leaves and cotyledons.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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DOT4 has DYW deaminase domain and is required for single RNA editing events in chloroplasts.
Title: Identification of two pentatricopeptide repeat genes required for RNA editing and zinc binding by C-terminal cytidine deaminase-like domains.

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NM_117991.3

Function	Evidence Code	Pubs
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chloroplast RNA modification	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cotyledon vascular tissue pattern formation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within leaf development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within leaf vascular tissue pattern formation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within phloem or xylem histogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	IMP Inferred from Mutant Phenotype more info	PubMed

NP_193610.1

DEFECTIVELY ORGANIZED TRIBUTARIES 4 (DOT4); INVOLVED IN: cotyledon vascular tissue pattern formation, phloem or xylem histogenesis, leaf vascular tissue pattern formation, leaf development; LOCATED IN: chloroplast; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT5G16860.1); Has 49728 Blast hits to 14531 proteins in 279 species: Archae - 0; Bacteria - 13; Metazoa - 210; Fungi - 140; Plants - 48642; Viruses - 0; Other Eukaryotes - 723 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain