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    Microsomal signal peptidase 12 kDa subunit (SPC12) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816774, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Microsomal signal peptidase 12 kDa subunit (SPC12)
    Primary source
    TAIR:AT2G22425
    Locus tag
    AT2G22425
    See related
    Araport:AT2G22425
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (9514695..9515674)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene SLOW GROWTH 1 Neighboring gene Peroxidase superfamily protein Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene homeobox protein 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197
    3. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001084473.2
    NM_127807.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal peptide processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of signal peptidase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Microsomal signal peptidase 12 kDa subunit (SPC12)
    NP_001077942.1
    • Microsomal signal peptidase 12 kDa subunit (SPC12); FUNCTIONS IN: peptidase activity; INVOLVED IN: signal peptide processing; LOCATED IN: endomembrane system, integral to membrane, signal peptidase complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Microsomal signal peptidase 12kDa subunit (InterPro:IPR009542); BEST Arabidopsis thaliana protein match is: Microsomal signal peptidase 12 kDa subunit (SPC12) (TAIR:AT4G40042.1); Has 315 Blast hits to 315 proteins in 147 species: Archae - 0; Bacteria - 0; Metazoa - 142; Fungi - 81; Plants - 67; Viruses - 0; Other Eukaryotes - 25 (source: NCBI BLink).
    NP_565535.1
    • Microsomal signal peptidase 12 kDa subunit (SPC12); FUNCTIONS IN: peptidase activity; INVOLVED IN: signal peptide processing; LOCATED IN: endomembrane system, signal peptidase complex, integral to membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Microsomal signal peptidase 12kDa subunit (InterPro:IPR009542); BEST Arabidopsis thaliana protein match is: Microsomal signal peptidase 12 kDa subunit (SPC12) (TAIR:AT4G40042.1); Has 315 Blast hits to 315 proteins in 147 species: Archae - 0; Bacteria - 0; Metazoa - 142; Fungi - 81; Plants - 67; Viruses - 0; Other Eukaryotes - 25 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9514695..9515674
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127807.4 → NP_565535.1  Microsomal signal peptidase 12 kDa subunit (SPC12) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565535.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7G9Y5, Q944J0
      UniProtKB/TrEMBL
      A0A178VPE5, A0A5S9X0E2
      Conserved Domains (1) summary
      pfam06645
      Location:1 → 71
      SPC12; Microsomal signal peptidase 12 kDa subunit (SPC12)

    2. NM_001084473.2 → NP_001077942.1  Microsomal signal peptidase 12 kDa subunit (SPC12) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077942.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7G9Y5, Q944J0
      UniProtKB/TrEMBL
      A0A178VPE5, A0A5S9X0E2
      Conserved Domains (1) summary
      pfam06645
      Location:1 → 71
      SPC12; Microsomal signal peptidase 12 kDa subunit (SPC12)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q944J0.1

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