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    HRS1 myb-like transcription factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837890, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HRS1
    Official Full Name
    myb-like transcription factor family protein
    Primary source
    TAIR:AT1G13300
    Locus tag
    AT1G13300
    See related
    Araport:AT1G13300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    HYPERSENSITIVITY TO LOW PI-ELICITED PRIMARY ROOT SHORTENING 1; HYPERSENSITIVITY TO LOW PI-ELICITED PRIMARY ROOT SHORTENING 1; T6J4.6; T6J4_6
    Summary
    Overexpression confers hypersensitivity to low phosphate-elicited inhibition of primary root growth.
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    Genomic context

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    See HRS1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (4556878..4558793)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene allene oxide cyclase 4 Neighboring gene C2H2-like zinc finger protein Neighboring gene Endosomal targeting BRO1-like domain-containing protein Neighboring gene protein phosphatase 2A subunit A3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis thaliana AtHRS1 gene is involved in the response to Heterodera schachtii infection and its overexpression hampers development of syncytia and involves a jasmonic acid-dependent mechanism. Wiśniewska A, et al. J Plant Physiol, 2022 May. PMID 35338957
    2. AtNIGT1/HRS1 integrates nitrate and phosphate signals at the Arabidopsis root tip. Medici A, et al. Nat Commun, 2015 Feb 27. PMID 25723764, Free PMC Article
    3. HRS1 acts as a negative regulator of abscisic acid signaling to promote timely germination of Arabidopsis seeds. Wu C, et al. PLoS One, 2012. PMID 22545134, Free PMC Article
    4. Overexpressing HRS1 confers hypersensitivity to low phosphate-elicited inhibition of primary root growth in Arabidopsis thaliana. Liu H, et al. J Integr Plant Biol, 2009 Apr. PMID 19341407
    5. Nitrate-inducible NIGT1 proteins modulate phosphate uptake and starvation signalling via transcriptional regulation of SPX genes. Ueda Y, et al. Plant J, 2020 May. PMID 31811679

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis thaliana AtHRS1 gene is involved in the response to Heterodera schachtii infection and its overexpression hampers development of syncytia and involves a jasmonic acid-dependent mechanism.
      Title: Arabidopsis thaliana AtHRS1 gene is involved in the response to Heterodera schachtii infection and its overexpression hampers development of syncytia and involves a jasmonic acid-dependent mechanism.
    2. We propose that NIGT1/HRS1s are major regulators of N starvation responses that play an important role in optimizing N acquisition and utilization under fluctuating N conditions.
      Title: Repression of Nitrogen Starvation Responses by Members of the Arabidopsis GARP-Type Transcription Factor NIGT1/HRS1 Subfamily.
    3. NO3- and P signalling converge via double transcriptional and post-transcriptional control of the same protein, HRS1.
      Title: AtNIGT1/HRS1 integrates nitrate and phosphate signals at the Arabidopsis root tip.
    4. HRS1 knockout mutant (hrs1-1) exhibited significant germination delays on either normal medium or those supplemented with abscisic acid (ABA) or sodium chloride (NaCl), with the magnitude of the delay being substantially larger on the latter media.
      Title: HRS1 acts as a negative regulator of abscisic acid signaling to promote timely germination of Arabidopsis seeds.
    5. HRS1 may be involved in the modulation of primary root and root hair growth in phopshate-deprived Arabidopsis seedlings.
      Title: Overexpressing HRS1 confers hypersensitivity to low phosphate-elicited inhibition of primary root growth in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101201.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription repressor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within cellular response to nitrogen compound IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to phosphate starvation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within primary root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of response to nutrient levels IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    myb-like transcription factor family protein
    NP_563926.1
    • HYPERSENSITIVITY TO LOW PI-ELICITED PRIMARY ROOT SHORTENING 1 (HRS1); CONTAINS InterPro DOMAIN/s: Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: myb-like transcription factor family protein (TAIR:AT3G25790.1); Has 1648 Blast hits to 1627 proteins in 64 species: Archae - 0; Bacteria - 2; Metazoa - 2; Fungi - 2; Plants - 1613; Viruses - 8; Other Eukaryotes - 21 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      4556878..4558793
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101201.2 → NP_563926.1  myb-like transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563926.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FX67
      UniProtKB/TrEMBL
      A0A178W2E4, A0A5S9U7A4, A0A654E9B5
      Conserved Domains (1) summary
      TIGR01557
      Location:181 → 237
      myb_SHAQKYF; myb-like DNA-binding domain, SHAQKYF class
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FX67.1

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