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    LRR and NB-ARC domains-containing disease resistance protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826674, updated on 18-Sep-2024

    Summary

    Official Full Name
    LRR and NB-ARC domains-containing disease resistance protein
    Primary source
    TAIR:AT4G10780
    Locus tag
    AT4G10780
    See related
    Araport:AT4G10780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T12H20.8; T12H20_8
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    Genomic context

    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (6634460..6637457, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene SCR-like 21 Neighboring gene oligopeptide transporter 7 Neighboring gene UBX domain-containing protein Neighboring gene BTB/POZ domain protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_117146.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    LRR and NB-ARC domains-containing disease resistance protein
    NP_192816.1
    • LRR and NB-ARC domains-containing disease resistance protein; FUNCTIONS IN: nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: N-terminal protein myristoylation, defense response, apoptosis; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (CC-NBS-LRR class) family (TAIR:AT1G12220.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      6634460..6637457 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001340685.1NP_001328297.1  LRR and NB-ARC domains-containing disease resistance protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B4B5, A0A654FN21
    2. NM_117146.1NP_192816.1  LRR and NB-ARC domains-containing disease resistance protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192816.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82484
      UniProtKB/TrEMBL
      A0A654FN21
      Conserved Domains (5) summary
      cd00009
      Location:178290
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      cd00116
      Location:519646
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:516537
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00931
      Location:157436
      NB-ARC; NB-ARC domain
      pfam13855
      Location:536597
      LRR_8; Leucine rich repeat