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    CIMG_01729 aconitate hydratase, mitochondrial [ Coccidioides immitis RS ]

    Gene ID: 4566915, updated on 31-Oct-2024

    Summary

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    Gene symbol
    CIMG_01729
    Gene description
    aconitate hydratase, mitochondrial
    Locus tag
    CIMG_01729
    See related
    FungiDB:CIMG_01729; VEuPathDB:CIMG_01729
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Coccidioides immitis RS (strain: RS)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides
    Orthologs
    Aspergillus fumigatus all
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    Genomic context

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    See CIMG_01729 in Genome Data Viewer
    Location:
    chromosome: Unknown
    Exon count:
    8

    NW_004504310.1Genomic Context describing neighboring genes Neighboring gene alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1 Neighboring gene metallo-beta-lactamase Neighboring gene C6 zinc finger domain-containing protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004504310.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables aconitate hydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aconitate hydratase, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NW_004504310.1 Reference assembly

      Range
      3907459..3911150 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001247957.2 → XP_001247958.1  aconitate hydratase, mitochondrial [Coccidioides immitis RS]

      See identical proteins and their annotated locations for XP_001247958.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0J7AWH8, A0A0J8RS14, A0A0J8TRD7, J3KJT2
      Conserved Domains (3) summary
      cd01584
      Location:100 → 510
      AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
      TIGR01340
      Location:50 → 779
      aconitase_mito; aconitate hydratase, mitochondrial
      cl00215
      Location:592 → 739
      Aconitase_swivel; Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme ...
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials