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    oxsr1.L oxidative stress responsive kinase 1 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 446749, updated on 4-Nov-2024

    Summary

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    Official Symbol
    oxsr1.L
    Official Full Name
    oxidative stress responsive kinase 1 L homeolog
    Primary source
    Xenbase:XB-GENE-5824599
    Locus tag
    XELAEV_18030632mg
    See related
    EnsemblRapid:ENSXLAG00005029179 AllianceGenome:Xenbase:XB-GENE-5824599
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    dcht; pask; spak; stk39; stk39.L
    Summary
    Predicted to enable ATP binding activity and histone H2AS1 kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoplasm. Orthologous to human OXSR1 (oxidative stress responsive kinase 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See oxsr1.L in Genome Data Viewer
    Location:
    chromosome: 6L
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (11188247..11254277)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (8730738..8797380)

    Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene cryptochrome DASH L homeolog Neighboring gene myeloid differentiation primary response 88 L homeolog Neighboring gene lamina-associated polypeptide 2-like Neighboring gene solute carrier family 22 member 13 L homeolog Neighboring gene xin actin binding repeat containing 1 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC78970

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    oxidative stress responsive kinase 1 L homeolog
    Names
    OSR1 kinase
    serine threonine kinase 39 (STE20/SPS1 homolog)
    serine threonine kinase 39 (STE20/SPS1 homolog, yeast)
    serine/threonine kinase 39 L homeolog
    NP_001086914.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001093445.1 → NP_001086914.1  oxidative stress responsive kinase 1 L homeolog

      See identical proteins and their annotated locations for NP_001086914.1

      Status: PROVISIONAL

      Source sequence(s)
      BC127406
      UniProtKB/TrEMBL
      A0A974HEX0, A0JPG0, Q6DD77
      Related
      ENSXLAP00005087506.1, ENSXLAT00005089168.1
      Conserved Domains (2) summary
      cd06610
      Location:19 → 295
      STKc_OSR1_SPAK; Catalytic domain of the Serine/Threonine Kinases, Oxidative stress response kinase and Ste20-related proline alanine-rich kinase
      pfam12202
      Location:435 → 492
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      11188247..11254277
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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