mycn.S MYCN proto-oncogene, bHLH transcription factor S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: mycn.S
Official Full Name: MYCN proto-oncogene, bHLH transcription factor S homeolog
Primary source: Xenbase:XB-GENE-478863
Locus tag: XELAEV_18030101mg
See related: EnsemblRapid:ENSXLAG00005018354
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: mycn; nmyc; N-myc; XNmyc; mycna; XN-myc; mycn-a; mycn-b; xN-myc1
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5S

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5S	NC_054380.1 (128655625..128662924)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5S	NC_030733.1 (121931694..121938991)

Chromosome 5S - NC_054380.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: MYCN proto-oncogene, bHLH transcription factor S homeolog

Names: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog S homeolog; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived, a

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001086880.1 → NP_001080349.1 MYCN proto-oncogene, bHLH transcription factor S homeolog

See identical proteins and their annotated locations for NP_001080349.1

Status: PROVISIONAL

Source sequence(s)

BC043747

UniProtKB/TrEMBL

A0A974HIN0, Q7ZYK5

Related

ENSXLAP00005054220.1, ENSXLAT00005055394.1

Conserved Domains (2) summary

cd00083
Location:354 → 410

HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

pfam01056
Location:2 → 347

Myc_N; Myc amino-terminal region