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    Klhl36 kelch-like 36 [ Mus musculus (house mouse) ]

    Gene ID: 234796, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Klhl36provided by MGI
    Official Full Name
    kelch-like 36provided by MGI
    Primary source
    MGI:MGI:2385305
    See related
    Ensembl:ENSMUSG00000031828 AllianceGenome:MGI:2385305
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable cullin family protein binding activity. Predicted to be involved in protein ubiquitination. Orthologous to human KLHL36 (kelch like family member 36). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 21.9), kidney adult (RPKM 16.6) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Klhl36 in Genome Data Viewer
    Location:
    8 E1; 8 68.52 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (120588970..120603728)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (119862231..119876989)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E113 Neighboring gene MTOR associated protein, eak-7 homolog Neighboring gene coactosin like F-actin binding protein 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:122361795-122361952 Neighboring gene STARR-positive B cell enhancer ABC_E2880 Neighboring gene STARR-positive B cell enhancer mm9_chr8:122367394-122367695 Neighboring gene STARR-positive B cell enhancer ABC_E2881 Neighboring gene predicted gene, 53464 Neighboring gene STARR-positive B cell enhancer mm9_chr8:122434591-122434892 Neighboring gene ubiquitin specific peptidase 10 Neighboring gene STARR-seq mESC enhancer starr_22870

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Little skate genome provides insights into genetic programs essential for limb-based locomotion. Yoo D, et al. Elife, 2022 Oct 26. PMID 36288084, Free PMC Article
    2. Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. Ling KH, et al. Genome Biol, 2009. PMID 19799774, Free PMC Article
    3. Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Apr 30. PMID 15449545
    4. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC37805

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cullin family protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cullin family protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cullin family protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    kelch-like protein 36

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146219.1 → NP_666331.1  kelch-like protein 36

      See identical proteins and their annotated locations for NP_666331.1

      Status: PROVISIONAL

      Source sequence(s)
      BC025816
      Consensus CDS
      CCDS22713.1
      UniProtKB/Swiss-Prot
      Q3U0B9, Q6KAS2, Q8R124
      Related
      ENSMUSP00000034287.9, ENSMUST00000034287.10
      Conserved Domains (6) summary
      smart00612
      Location:545 → 591
      Kelch; Kelch domain
      smart00875
      Location:147 → 247
      BACK; BTB And C-terminal Kelch
      PHA03098
      Location:58 → 583
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:333 → 381
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:35 → 138
      BTB; BTB/POZ domain
      pfam01344
      Location:332 → 382
      Kelch_1; Kelch motif

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      120588970..120603728
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001778433.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8R124.1 GenPept UniProtKB/Swiss-Prot:Q8R124

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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