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    Gm12258 predicted gene 12258 [ Mus musculus (house mouse) ]

    Gene ID: 108167848, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Gm12258provided by MGI
    Official Full Name
    predicted gene 12258provided by MGI
    Primary source
    MGI:MGI:3651534
    See related
    Ensembl:ENSMUSG00000072915 AllianceGenome:MGI:3651534
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 9.3), CNS E14 (RPKM 9.0) and 23 other tissues See more
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    Genomic context

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    See Gm12258 in Genome Data Viewer
    Location:
    11 B1.3; 11 36.33 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (58737971..58752783)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (58847162..58861957)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily AF member 1 Neighboring gene STARR-positive B cell enhancer ABC_E588 Neighboring gene olfactory receptor family 9 subfamily E member 1 Neighboring gene RIKEN cDNA 2810021J22 gene Neighboring gene STARR-positive B cell enhancer ABC_E9824 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:58697199-58697308 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:58697335-58697545 Neighboring gene zinc finger protein 39 Neighboring gene STARR-positive B cell enhancer ABC_E2990 Neighboring gene predicted gene 12257

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC108167848
    Names
    part of a novel protein
    zinc finger protein 717-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001372581.1 → NP_001359510.1  uncharacterized protein LOC108167848 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL662903, CN460644
      Consensus CDS
      CCDS88162.1
      UniProtKB/TrEMBL
      Q5NC63
      Related
      ENSMUSP00000117644.3, ENSMUST00000139337.3
      Conserved Domains (5) summary
      smart00349
      Location:8 → 67
      KRAB; krueppel associated box
      COG5048
      Location:412 → 608
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:488 → 508
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:249 → 269
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:598 → 620
      zf-C2H2; Zinc finger, C2H2 type

    2. NM_001372582.1 → NP_001359511.1  uncharacterized protein LOC108167848 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL662903
      Conserved Domains (5) summary
      COG5048
      Location:376 → 572
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:452 → 472
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:213 → 233
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:562 → 584
      zf-C2H2; Zinc finger, C2H2 type
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      58737971..58752783
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156222.1 → XP_036012115.1  uncharacterized protein LOC108167848 isoform X1

      Conserved Domains (5) summary
      COG5048
      Location:376 → 572
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:452 → 472
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:213 → 233
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:562 → 584
      zf-C2H2; Zinc finger, C2H2 type
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    Nucleotide Protein Strain
    Heading Accession and Version

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