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groEL molecular chaperone GroEL [ Streptococcus pyogenes MGAS8232 ]

Gene ID: 994320, discontinued on 3-Feb-2015
  • All Gene records for this genome have been discontinued due to a change in scope for prokaryotic genomes in Gene. At the time this Gene record was discontinued, the RefSeq genome was re-annotated with the following features at this location:

Summary

Gene symbol
groEL
Gene description
molecular chaperone GroEL
Locus tag
spyM18_2129
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Streptococcus pyogenes MGAS8232 (strain: MGAS8232)
Lineage
Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
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General protein information

Names
molecular chaperone GroEL
NP_608082.1
  • 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003485.1 Reference assembly

    Range
    1778092..1779723 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_608082.1 molecular chaperone GroEL [Streptococcus pyogenes MGAS8232]

    Status: REVIEWED