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ZNF536 zinc finger protein 536 [ Homo sapiens (human) ]

Gene ID: 9745, updated on 2-Nov-2024

Summary

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Official Symbol
ZNF536provided by HGNC
Official Full Name
zinc finger protein 536provided by HGNC
Primary source
HGNC:HGNC:29025
See related
Ensembl:ENSG00000198597 MIM:618037; AllianceGenome:HGNC:29025
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
The protein encoded by this gene is a highly conserved zinc finger protein. The encoded protein is most abundant in brain, where it negatively regulates neuronal differentiation. [provided by RefSeq, Sep 2015]
Expression
Biased expression in brain (RPKM 2.6), thyroid (RPKM 0.8) and 11 other tissues See more
Orthologs
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Genomic context

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See ZNF536 in Genome Data Viewer
Location:
19q12
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (30225592..30713586)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (32746044..33234121)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (30716499..31204493)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14426 Neighboring gene VISTA enhancer hs382 Neighboring gene uncharacterized LOC107985271 Neighboring gene VISTA enhancer hs721 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14427 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30583442-30583972 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30583973-30584501 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:30589624-30589867 Neighboring gene TATA-box binding protein associated factor 9 pseudogene 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30607607-30608158 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30608159-30608708 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:30648008-30648968 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10475 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30714014-30714514 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30714515-30715015 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10476 Neighboring gene VISTA enhancer hs858 Neighboring gene VISTA enhancer hs383 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:30811773-30812272 Neighboring gene VISTA enhancer hs430 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr19:30864335-30864836 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30866004-30866504 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30875860-30876360 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:30948561-30949071 Neighboring gene VISTA enhancer hs384 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:31042441-31042941 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:31044111-31044612 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:31055005-31055756 Neighboring gene uncharacterized LOC124904685 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:31182908-31183532 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:31183533-31184155 Neighboring gene MPRA-validated peak3430 silencer Neighboring gene uncharacterized LOC105372354 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:31210807-31211306 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:31224870-31226069 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:31297953-31298452 Neighboring gene long intergenic non-protein coding RNA 1834

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Characterization of zinc finger protein 536, a neuroendocrine regulator, using pan-cancer analysis. Zeng L, et al. Eur J Med Res, 2024 May 8. PMID 38720348, Free PMC Article
  2. Identification of the DNA binding specificity of the human ZNF219 protein and its function as a transcriptional repressor. Sakai T, et al. DNA Res, 2003 Aug 31. PMID 14621294
  3. ZNF536, a novel zinc finger protein specifically expressed in the brain, negatively regulates neuron differentiation by repressing retinoic acid-induced gene transcription. Qin Z, et al. Mol Cell Biol, 2009 Jul. PMID 19398580, Free PMC Article
  4. Functional genomic analysis of oligodendrocyte differentiation. Dugas JC, et al. J Neurosci, 2006 Oct 25. PMID 17065439, Free PMC Article
  5. Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment. Fransen E, et al. Eur J Hum Genet, 2015 Jan. PMID 24939585, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Characterization of zinc finger protein 536, a neuroendocrine regulator, using pan-cancer analysis.
    Title: Characterization of zinc finger protein 536, a neuroendocrine regulator, using pan-cancer analysis.
  2. ZFP536 promotes the late phase of oligodendrocyte differentiation.
    Title: Functional genomic analysis of oligodendrocyte differentiation.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.
EBI GWAS Catalog
Biological insights from 108 schizophrenia-associated genetic loci.
EBI GWAS Catalog
Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment.
EBI GWAS Catalog
Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
EBI GWAS Catalog
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
EBI GWAS Catalog
Genome-wide association with select biomarker traits in the Framingham Heart Study.
EBI GWAS Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

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Replication interactions

Interaction Pubs
Knockdown of zinc finger protein 536 (ZNF536) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA0390

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables retinoic acid-responsive element binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of retinoic acid receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 536

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001352260.2 → NP_001339189.1  zinc finger protein 536 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC011454, AC011478, AC011504, AC011532, DA205038, DT215826, HY151164, HY309977
    Consensus CDS
    CCDS92576.1
    UniProtKB/TrEMBL
    A0A994J7Z0, A7E228
    Related
    ENSP00000516233.1, ENST00000706150.1
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:753 → 773
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:765 → 787
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:779 → 802
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  2. NM_001376110.1 → NP_001363039.1  zinc finger protein 536 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC005597, AC006506, AC011454, AC011504, AC011532
    Consensus CDS
    CCDS92577.1
    UniProtKB/TrEMBL
    A7E228, K7EQN6
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:753 → 773
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:765 → 787
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:779 → 802
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  3. NM_001376111.1 → NP_001363040.1  zinc finger protein 536 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC005597, AC006506, AC011454, AC011504, AC011532
    Consensus CDS
    CCDS92577.1
    UniProtKB/TrEMBL
    A7E228, K7EQN6
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:753 → 773
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:765 → 787
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:779 → 802
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  4. NM_014717.3 → NP_055532.1  zinc finger protein 536 isoform 1

    See identical proteins and their annotated locations for NP_055532.1

    Status: REVIEWED

    Source sequence(s)
    AC011454, BC146757, HY151164
    Consensus CDS
    CCDS32984.1
    UniProtKB/Swiss-Prot
    A2RU18, O15090
    UniProtKB/TrEMBL
    A7E228
    Related
    ENSP00000347730.1, ENST00000355537.4
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:753 → 773
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:765 → 787
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:779 → 802
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    30225592..30713586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047439770.1 → XP_047295726.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  2. XM_011527554.3 → XP_011525856.1  zinc finger protein 536 isoform X1

    See identical proteins and their annotated locations for XP_011525856.1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  3. XM_047439763.1 → XP_047295719.1  zinc finger protein 536 isoform X1

  4. XM_047439779.1 → XP_047295735.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  5. XM_047439781.1 → XP_047295737.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  6. XM_047439774.1 → XP_047295730.1  zinc finger protein 536 isoform X4

  7. XM_047439775.1 → XP_047295731.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090
    Related
    ENSP00000516228.1, ENST00000706144.1

  8. XM_047439776.1 → XP_047295732.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  9. XM_017027532.2 → XP_016883021.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  10. XM_047439765.1 → XP_047295721.1  zinc finger protein 536 isoform X1

  11. XM_017027531.2 → XP_016883020.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  12. XM_047439764.1 → XP_047295720.1  zinc finger protein 536 isoform X1

  13. XM_047439767.1 → XP_047295723.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  14. XM_047439769.1 → XP_047295725.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  15. XM_047439778.1 → XP_047295734.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  16. XM_047439780.1 → XP_047295736.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  17. XM_047439785.1 → XP_047295741.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  18. XM_017027533.2 → XP_016883022.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  19. XM_047439772.1 → XP_047295728.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6
    Related
    ENSP00000467909.3, ENST00000592773.3

  20. XM_017027535.2 → XP_016883024.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  21. XM_047439783.1 → XP_047295739.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090
    Related
    ENSP00000516229.1, ENST00000706146.1

  22. XM_047439784.1 → XP_047295740.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  23. XM_047439773.1 → XP_047295729.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  24. XM_047439766.1 → XP_047295722.1  zinc finger protein 536 isoform X1

  25. XM_017027530.2 → XP_016883019.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  26. XM_024451807.2 → XP_024307575.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  27. XM_017027529.2 → XP_016883018.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  28. XM_047439768.1 → XP_047295724.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  29. XM_017027534.2 → XP_016883023.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  30. XM_017027527.2 → XP_016883016.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  31. XM_017027537.2 → XP_016883026.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    A7E228, K7EQN6
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:753 → 773
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:765 → 787
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:779 → 802
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  32. XM_017027528.2 → XP_016883017.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  33. XM_017027536.2 → XP_016883025.1  zinc finger protein 536 isoform X1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  34. XM_011527558.3 → XP_011525860.1  zinc finger protein 536 isoform X1

    See identical proteins and their annotated locations for XP_011525860.1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  35. XM_047439771.1 → XP_047295727.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  36. XM_047439782.1 → XP_047295738.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  37. XM_017027539.2 → XP_016883028.1  zinc finger protein 536 isoform X3

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  38. XM_017027542.2 → XP_016883031.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090
    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:753 → 773
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:765 → 787
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:779 → 802
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  39. XM_047439777.1 → XP_047295733.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  40. XM_047439786.1 → XP_047295742.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  41. XM_011527557.3 → XP_011525859.1  zinc finger protein 536 isoform X1

    See identical proteins and their annotated locations for XP_011525859.1

    UniProtKB/TrEMBL
    A7E228
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:132 → 152
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:145 → 169
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:808 → 831
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  42. XM_011527560.3 → XP_011525862.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    A7E228, K7EQN6
    Conserved Domains (6) summary
    COG5048
    Location:103 → 180
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:753 → 773
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:753 → 773
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:765 → 787
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:779 → 802
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam16606
    Location:657 → 737
    zf-C2H2_assoc; Unstructured conserved, between two C2H2-type zinc-fingers

  43. XM_017027543.3 → XP_016883032.1  zinc finger protein 536 isoform X6

    UniProtKB/TrEMBL
    A0A994J5Q4

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    32746044..33234121
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054322774.1 → XP_054178749.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  2. XM_054322754.1 → XP_054178729.1  zinc finger protein 536 isoform X1

  3. XM_054322753.1 → XP_054178728.1  zinc finger protein 536 isoform X1

  4. XM_054322786.1 → XP_054178761.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  5. XM_054322788.1 → XP_054178763.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  6. XM_054322780.1 → XP_054178755.1  zinc finger protein 536 isoform X4

  7. XM_054322782.1 → XP_054178757.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  8. XM_054322783.1 → XP_054178758.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  9. XM_054322765.1 → XP_054178740.1  zinc finger protein 536 isoform X1

  10. XM_054322760.1 → XP_054178735.1  zinc finger protein 536 isoform X1

  11. XM_054322756.1 → XP_054178731.1  zinc finger protein 536 isoform X1

  12. XM_054322758.1 → XP_054178733.1  zinc finger protein 536 isoform X1

  13. XM_054322771.1 → XP_054178746.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  14. XM_054322773.1 → XP_054178748.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  15. XM_054322785.1 → XP_054178760.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  16. XM_054322787.1 → XP_054178762.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  17. XM_054322792.1 → XP_054178767.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  18. XM_054322766.1 → XP_054178741.1  zinc finger protein 536 isoform X1

  19. XM_054322777.1 → XP_054178752.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  20. XM_054322762.1 → XP_054178737.1  zinc finger protein 536 isoform X1

  21. XM_054322790.1 → XP_054178765.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  22. XM_054322791.1 → XP_054178766.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  23. XM_054322778.1 → XP_054178753.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  24. XM_054322768.1 → XP_054178743.1  zinc finger protein 536 isoform X1

  25. XM_054322757.1 → XP_054178732.1  zinc finger protein 536 isoform X1

  26. XM_054322764.1 → XP_054178739.1  zinc finger protein 536 isoform X1

  27. XM_054322759.1 → XP_054178734.1  zinc finger protein 536 isoform X1

  28. XM_054322772.1 → XP_054178747.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  29. XM_054322767.1 → XP_054178742.1  zinc finger protein 536 isoform X1

  30. XM_054322755.1 → XP_054178730.1  zinc finger protein 536 isoform X1

  31. XM_054322770.1 → XP_054178745.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  32. XM_054322752.1 → XP_054178727.1  zinc finger protein 536 isoform X1

  33. XM_054322769.1 → XP_054178744.1  zinc finger protein 536 isoform X1

  34. XM_054322763.1 → XP_054178738.1  zinc finger protein 536 isoform X1

  35. XM_054322775.1 → XP_054178750.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  36. XM_054322789.1 → XP_054178764.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  37. XM_054322779.1 → XP_054178754.1  zinc finger protein 536 isoform X3

  38. XM_054322781.1 → XP_054178756.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  39. XM_054322784.1 → XP_054178759.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  40. XM_054322793.1 → XP_054178768.1  zinc finger protein 536 isoform X5

    UniProtKB/Swiss-Prot
    A2RU18, O15090

  41. XM_054322761.1 → XP_054178736.1  zinc finger protein 536 isoform X1

  42. XM_054322776.1 → XP_054178751.1  zinc finger protein 536 isoform X2

    UniProtKB/TrEMBL
    K7EQN6

  43. XM_054322794.1 → XP_054178769.1  zinc finger protein 536 isoform X6

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O15090.3 GenPept UniProtKB/Swiss-Prot:O15090

Gene LinkOut

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