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cpdB 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948729, updated on 19-Sep-2024

Summary

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Official Symbol
cpdB
Official Full Name
2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase
Primary source
ECOCYC:EG10160
Locus tag
b4213
See related
ASAP:ABE-0013782
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4209
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Genomic context

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Sequence:
NC_000913.3 (4434622..4436565, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene NAD(P)H:quinone oxidoreductase Neighboring gene putative transcriptional regulator YtfH Neighboring gene 3'(2'),5'-bisphosphate nucleotidase Neighboring gene protein YtfI

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation of Escherichia coli mutants (cpdB) deficient in periplasmic 2':3'-cyclic phosphodiesterase and genetic mapping of the cpdB locus. Beacham IR, et al. J Gen Microbiol, 1980 Jul. PMID 6251162
  2. Transcription and regulation of the cpdB gene in Escherichia coli K12 and Salmonella typhimurium LT2: evidence for modulation of constitutive promoters by cyclic AMP-CRP complex. Liu J, et al. Mol Gen Genet, 1990 Jun. PMID 2172762
  3. Localization of the Escherichia coli amtA gene to 95.8 minutes. Jayakumar A, et al. J Bacteriol, 1991 Mar. PMID 1999381, Free PMC Article
  4. Release of periplasmic enzymes from Escherichia coli by penicillin-ethylenediaminetetraacetate treatment. Ananthaswamy HN. J Bacteriol, 1977 Aug. PMID 195932, Free PMC Article
  5. Comparison of the large-scale periplasmic proteomes of the Escherichia coli K-12 and B strains. Han MJ, et al. J Biosci Bioeng, 2014 Apr. PMID 24140104

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
  
enables 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables 3'-nucleotidase activity IEA
Inferred from Electronic Annotation
more info
  
enables 3'-nucleotidase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotidase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in nucleotide catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase
NP_418634.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4434622..4436565 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418634.1 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418634.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1V2GK32, A0A8S7ECV0, A0A8S7S292
    Conserved Domains (1) summary
    PRK09420
    Location:1 → 647
    cpdB; bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase
Nucleotide Protein
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