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nrfE putative cytochrome c-type biogenesis protein NrfE [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948579, updated on 10-Oct-2024

Summary

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Official Symbol
nrfE
Official Full Name
putative cytochrome c-type biogenesis protein NrfE
Primary source
ECOCYC:EG11948
Locus tag
b4074
See related
ASAP:ABE-0013350
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4067; yjcL
Summary
NrfE is a membrane-spanning protein that is essential for NirA activity. [More information is available at EcoCyc: EG11948].
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Genomic context

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Sequence:
NC_000913.3 (4291512..4293170)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene periplasmic nitrite reductase penta-heme c-type cytochrome Neighboring gene putative menaquinol-cytochrome c reductase 4Fe-4S subunit Neighboring gene putative menaquinol-cytochrome c reductase subunit NrfD Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfF Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfG Neighboring gene glutamate/aspartate : H(+) symporter GltP

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of the formate dehydrogenases and genetic determinants of formate-dependent nitrite reduction by Escherichia coli K12. Darwin A, et al. J Gen Microbiol, 1993 Aug. PMID 8409924
  2. Involvement of products of the nrfEFG genes in the covalent attachment of haem c to a novel cysteine-lysine motif in the cytochrome c552 nitrite reductase from Escherichia coli. Eaves DJ, et al. Mol Microbiol, 1998 Apr. PMID 9593308
  3. Nitric oxide formation by Escherichia coli. Dependence on nitrite reductase, the NO-sensing regulator Fnr, and flavohemoglobin Hmp. Corker H, et al. J Biol Chem, 2003 Aug 22. PMID 12783887
  4. The role of the genes nrf EFG and ccmFH in cytochrome c biosynthesis in Escherichia coli. Grovc J, et al. Mol Gen Genet, 1996 Sep 13. PMID 8842153
  5. Nitric oxide-sensing mechanisms in Escherichia coli. Spiro S. Biochem Soc Trans, 2006 Feb. PMID 16417522

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables heme transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytochrome complex assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in heme transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative cytochrome c-type biogenesis protein NrfE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4291512..4293170
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418498.1 putative cytochrome c-type biogenesis protein NrfE [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418498.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1X3HYY0, A0A366VPV2, A0A828Q2H5, A0A8S7RXR1, A0AAD2NUX7, A0AAN3N843, B7NG17
    Conserved Domains (1) summary
    PRK10369
    Location:1 → 552
    PRK10369; heme lyase subunit NrfE; Provisional
Nucleotide Protein
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