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pdeC c-di-GMP phosphodiesterase PdeC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948568, updated on 19-Sep-2024

Summary

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Official Symbol
pdeC
Official Full Name
c-di-GMP phosphodiesterase PdeC
Primary source
ECOCYC:EG11938
Locus tag
b4061
See related
ASAP:ABE-0013309
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4053; yjcC
Summary
YjcC has a C-terminal putative cyclic-di-GMP phosphodiesterase EAL domain. [More information is available at EcoGene: EG11938]. YjcC is an inner membrane protein with two predicted transmembrane domains. [More information is available at EcoCyc: EG11938].
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Genomic context

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Sequence:
NC_000913.3 (4275471..4277057)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ssDNA-binding protein Neighboring gene uncharacterized protein YjcB Neighboring gene DNA-binding transcriptional dual regulator SoxS Neighboring gene DNA-binding transcriptional dual regulator SoxR Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Second messenger signalling governs Escherichia coli biofilm induction upon ribosomal stress. Boehm A, et al. Mol Microbiol, 2009 Jun. PMID 19460094
  2. Expression and Genetic Activation of Cyclic Di-GMP-Specific Phosphodiesterases in Escherichia coli. Reinders A, et al. J Bacteriol, 2016 Feb 1. PMID 26553851, Free PMC Article
  3. Transmembrane redox control and proteolysis of PdeC, a novel type of c-di-GMP phosphodiesterase. Herbst S, et al. EMBO J, 2018 Apr 13. PMID 29514851, Free PMC Article
  4. C-di-GMP: the dawning of a novel bacterial signalling system. Römling U, et al. Mol Microbiol, 2005 Aug. PMID 16045609
  5. Gene expression patterns and differential input into curli fimbriae regulation of all GGDEF/EAL domain proteins in Escherichia coli. Sommerfeldt N, et al. Microbiology (Reading), 2009 Apr. PMID 19332833

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables cyclic-guanylate-specific phosphodiesterase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables cyclic-guanylate-specific phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
  
enables cyclic-guanylate-specific phosphodiesterase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in outer membrane-bounded periplasmic space RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
c-di-GMP phosphodiesterase PdeC
NP_418485.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4275471..4277057
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418485.1 c-di-GMP phosphodiesterase PdeC [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418485.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7SU89
    Conserved Domains (1) summary
    COG4943
    Location:1 → 526
    YjcC; Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain [Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version

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