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malQ 4-alpha-glucanotransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947923, updated on 19-Sep-2024

Summary

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Official Symbol
malQ
Official Full Name
4-alpha-glucanotransferase
Primary source
ECOCYC:EG10561
Locus tag
b3416
See related
ASAP:ABE-0011151
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3403; malA
Summary
MalT regulon. [More information is available at EcoGene: EG10561]. Amylomaltase was first described as a maltose-inducible enzyme that catalyzes a reversible transglycosidase reaction . [More information is available at EcoCyc: EG10561].
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Genomic context

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Sequence:
NC_000913.3 (3547986..3550070, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene iron-sulfur cluster carrier protein NfuA Neighboring gene high-affinity gluconate transporter Neighboring gene maltodextrin phosphorylase Neighboring gene DNA-binding transcriptional activator MalT

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the Transglycosylation Reaction of 4-α-Glucanotransferase (MalQ) and Its Role in Glycogen Breakdown in Escherichia coli. Nguyen DHD, et al. J Microbiol Biotechnol, 2019 Mar 28. PMID 30691252
  2. The action pattern of amylomaltase from Escherichia coli. Palmer TN, et al. Eur J Biochem, 1976 Oct 1. PMID 791642
  3. Direct utilization of maltose by Escherichia coli. DOUDOROFF M, et al. J Biol Chem, 1949 Jun. PMID 18150023
  4. Genetic analysis of the maltose A region in Escherichia coli. Hatfield D, et al. J Bacteriol, 1969 May. PMID 4891257, Free PMC Article
  5. Nonsense mutations in the maltose A region of the genetic map of Escherichia coli. Hatfield D, et al. J Bacteriol, 1969 Dec. PMID 4902812, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The action of MalQ on maltose or maltodextrin can lead to the formation of glycogen and that MalP controls (inhibits) this pathway.
    Title: Role of maltose enzymes in glycogen synthesis by Escherichia coli.
  2. The fact that glk malQ+ mutants showed elevated mal gene expression finds its explanation in the reduced ability to remove glucose from MalQ-catalyzed maltodextrin formation and is caused by a metabolically induced MalQ- phenotype.
    Title: Glucose- and glucokinase-controlled mal gene expression in Escherichia coli.
  3. A comparison of ATPHS2 and DPE2 from A. thaliana with MalP and MalQ from E. coli is presented.
    Title: The role of cytosolic alpha-glucan phosphorylase in maltose metabolism and the comparison of amylomaltase in Arabidopsis and Escherichia coli.
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Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4-alpha-glucanotransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 4-alpha-glucanotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables 4-alpha-glucanotransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glycogen biosynthetic process EXP
Inferred from Experiment
more info
 PubMed 
acts_upstream_of_or_within glycogen catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within maltose catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within maltose catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
4-alpha-glucanotransferase
NP_417875.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3547986..3550070 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417875.1 4-alpha-glucanotransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417875.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1V2GHL0, A0A376WSK2, A0A6M9WXH2
    Conserved Domains (1) summary
    PRK11052
    Location:1 → 684
    malQ; 4-alpha-glucanotransferase; Provisional
Nucleotide Protein
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Gene LinkOut

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