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tdcF putative enamine/imine deaminase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947624, updated on 19-Sep-2024

Summary

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Official Symbol
tdcF
Official Full Name
putative enamine/imine deaminase
Primary source
ECOCYC:G7626
Locus tag
b3113
See related
ASAP:ABE-0010240
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3102; yhaR
Summary
YjgF, RutC, TdcF, YoaB and YjgH are paralogs and members of a highly conserved YjgF family (pfam:PF01042) with diverse mutant phenotypes and unknown molecular function; the family members form homotrimers, some binding 2-ketoglutarate or related compounds. [More information is available at EcoGene: EG12757]. TdcF has been crystallized for structural studies . [More information is available at EcoCyc: G7626].
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Genomic context

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Sequence:
NC_000913.3 (3259721..3260110, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene cysteine detoxification protein CyuP Neighboring gene L-serine deaminase III Neighboring gene 2-ketobutyrate formate-lyase/pyruvate formate-lyase 4 Neighboring gene propionate kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystallization and preliminary X-ray analysis of the E. coli hypothetical protein TdcF. Burman JD, et al. Acta Crystallogr D Biol Crystallogr, 2003 Jun. PMID 12777779
  2. The tdcE gene in Escherichia coli strain W3110 is separated from the rest of the tdc operon by insertion of IS5 elements. Hesslinger C, et al. DNA Seq, 1998. PMID 10520749
  3. Structure and function of enzymes involved in the anaerobic degradation of L-threonine to propionate. Simanshu DK, et al. J Biosci, 2007 Sep. PMID 17954980
  4. A novel mechanism controls anaerobic and catabolite regulation of the Escherichia coli tdc operon. Sawers G. Mol Microbiol, 2001 Mar. PMID 11251844
  5. Physical map location of the tdc operon of Escherichia coli. Schweizer HP, et al. J Bacteriol, 1990 Jun. PMID 2188941, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-threonine catabolic process to propionate IEA
Inferred from Electronic Annotation
more info
  
involved_in threonine metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative enamine/imine deaminase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3259721..3260110 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417583.4 putative enamine/imine deaminase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417583.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376FWW7, A0A376MIU5, A0A5B9AS85, A0A6L7CM47, A0A895NMV0
    Conserved Domains (1) summary
    PRK11401
    Location:1 → 129
    PRK11401; enamine/imine deaminase
Nucleotide Protein
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