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fhuD iron(III) hydroxamate ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947510, updated on 19-Sep-2024

Summary

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Official Symbol
fhuD
Official Full Name
iron(III) hydroxamate ABC transporter periplasmic binding protein
Primary source
ECOCYC:EG10305
Locus tag
b0152
See related
ASAP:ABE-0000524
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0151
Summary
Verified Tat substrate: [More information is available at EcoGene: EG10305]. The FhuBCD ATP-dependent iron (III) hydroxamate transporter is a member of the ATP-Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10305].
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Genomic context

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Sequence:
NC_000913.3 (170575..171465)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ferrichrome outer membrane transporter/phage receptor Neighboring gene iron(III) hydroxamate ABC transporter ATP binding subunit Neighboring gene iron(III) hydroxamate ABC transporter membrane subunit Neighboring gene glutamate-1-semialdehyde 2,1-aminomutase Neighboring gene protein YadX

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular dynamics simulations of the periplasmic ferric-hydroxamate binding protein FhuD. Krewulak KD, et al. Biometals, 2005 Aug. PMID 16158230
  2. In vivo reconstitution of an active siderophore transport system by a binding protein derivative lacking a signal sequence. Rohrback MR, et al. Mol Gen Genet, 1995 Jul 22. PMID 7651325
  3. The structure of the ferric siderophore binding protein FhuD complexed with gallichrome. Clarke TE, et al. Nat Struct Biol, 2000 Apr. PMID 10742172
  4. X-ray crystallographic structures of the Escherichia coli periplasmic protein FhuD bound to hydroxamate-type siderophores and the antibiotic albomycin. Clarke TE, et al. J Biol Chem, 2002 Apr 19. PMID 11805094
  5. Ferric hydroxamate binding protein FhuD from Escherichia coli: mutants in conserved and non-conserved regions. Clarke TE, et al. Biometals, 2002 Jun. PMID 12046920

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within ferric-hydroxamate import into cell EXP
Inferred from Experiment
more info
 PubMed 
involved_in iron ion import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
iron(III) hydroxamate ABC transporter periplasmic binding protein
NP_414694.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    170575..171465
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414694.1 iron(III) hydroxamate ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414694.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H2V481, A0A192CIE5, A0AA36P5F9, Q1RG36
    Conserved Domains (1) summary
    PRK10576
    Location:4 → 295
    PRK10576; Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD
Nucleotide Protein
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