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cyoC cytochrome bo3 subunit 3 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946897, updated on 6-Jun-2024

Summary

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Gene symbol
cyoC
Gene description
cytochrome bo3 subunit 3
Primary source
ASAP:ABE-0001491
Locus tag
b0430
See related
ECOCYC:EG10180
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0424
Summary
CyoC is subunit III of the cytochrome bo terminal oxidase complex encoded by cyoABCDE. [More information is available at EcoCyc: EG10180].
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Genomic context

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Sequence:
NC_000913.3 (448046..448660, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene heme O synthase Neighboring gene cytochrome bo3 subunit 4 Neighboring gene cytochrome bo3 subunit 1 Neighboring gene cytochrome bo3 subunit 2 Neighboring gene muropeptide:H(+) symporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Differential effects of glutamate-286 mutations in the aa(3)-type cytochrome c oxidase from Rhodobacter sphaeroides and the cytochrome bo(3) ubiquinol oxidase from Escherichia coli. Egawa T, et al. Biochim Biophys Acta, 2011 Oct. PMID 21684251, Free PMC Article
  2. Searching for the low affinity ubiquinone binding site in cytochrome bo(3) from Escherichia coli. Choi SK, et al. Biochim Biophys Acta Bioenerg, 2017 May. PMID 28235459
  3. Assembly of the cytochrome bo3 complex. Stenberg F, et al. J Mol Biol, 2007 Aug 17. PMID 17583738
  4. Magic-angle spinning solid-state NMR of a 144 kDa membrane protein complex: E. coli cytochrome bo3 oxidase. Frericks HL, et al. J Biomol NMR, 2006 Sep. PMID 16964530
  5. Characterization of the exchangeable protons in the immediate vicinity of the semiquinone radical at the QH site of the cytochrome bo3 from Escherichia coli. Yap LL, et al. J Biol Chem, 2006 Jun 23. PMID 16624801

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. No evidence of low affinity ubiquinone binding site in cytochrome bo3 from Escherichia coli.
    Title: Searching for the low affinity ubiquinone binding site in cytochrome bo(3) from Escherichia coli.
  2. Data suggest that in RsCcO(aa3), the E286 mutations severely perturb the active site, while he local structure around E286 in EcQO(bo3) is different, providing a rationale for the different effects of E286 mutations in the two enzymes.
    Title: Differential effects of glutamate-286 mutations in the aa(3)-type cytochrome c oxidase from Rhodobacter sphaeroides and the cytochrome bo(3) ubiquinol oxidase from Escherichia coli.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables cytochrome bo3 ubiquinol oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cytochrome bo3 ubiquinol oxidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables cytochrome bo3 ubiquinol oxidase activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to cytochrome-c oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cytochrome-c oxidase activity IEA
Inferred from Electronic Annotation
more info
  
enables electron transfer activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreduction-driven active transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables proton transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in aerobic electron transport chain IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within aerobic electron transport chain IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in aerobic electron transport chain IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in aerobic electron transport chain IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within aerobic respiration IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within aerobic respiration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in electron transport coupled proton transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within electron transport coupled proton transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in electron transport coupled proton transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of cytochrome o ubiquinol oxidase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytochrome o ubiquinol oxidase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytochrome o ubiquinol oxidase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytochrome bo3 subunit 3
NP_414964.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    448046..448660 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414964.1 cytochrome bo3 subunit 3 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414964.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S0G1L6
    Conserved Domains (1) summary
    PRK10663
    Location:1 → 204
    PRK10663; cytochrome o ubiquinol oxidase subunit III; Provisional
Nucleotide Protein
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