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xapB xanthosine:H(+) symporter XapB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946868, updated on 19-Sep-2024

Summary

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Official Symbol
xapB
Official Full Name
xanthosine:H(+) symporter XapB
Primary source
ECOCYC:EG13159
Locus tag
b2406
See related
ASAP:ABE-0007925
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2400
Summary
NupG, XapB and YegT are paralogs. [More information is available at EcoGene: EG13159]. XapB is a probable xanthosine transporter. [More information is available at EcoCyc: EG13159].
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Genomic context

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Sequence:
NC_000913.3 (2522729..2523985, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene DNA-binding transcriptional activator XapR Neighboring gene xanthosine phosphorylase Neighboring gene putative outer membrane porin YfeN

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Specificity and topology of the Escherichia coli xanthosine permease, a representative of the NHS subfamily of the major facilitator superfamily. Nørholm MH, et al. J Bacteriol, 2001 Aug. PMID 11466294, Free PMC Article
  2. Identification and characterization of genes (xapA, xapB, and xapR) involved in xanthosine catabolism in Escherichia coli. Seeger C, et al. J Bacteriol, 1995 Oct. PMID 7559336, Free PMC Article
  3. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212
  4. A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Marger MD, et al. Trends Biochem Sci, 1993 Jan. PMID 8438231
  5. The major facilitator superfamily. Saier MH Jr, et al. J Mol Microbiol Biotechnol, 1999 Nov. PMID 10943556

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables cytidine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleoside transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleoside transmembrane transporter activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables uridine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables xanthosine transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytidine transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nucleobase-containing small molecule metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleoside transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in nucleoside transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nucleoside transport ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in uridine transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in xanthosine transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
xanthosine:H(+) symporter XapB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2522729..2523985 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416901.1 xanthosine:H(+) symporter XapB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416901.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7TPD8
    Conserved Domains (1) summary
    TIGR00889
    Location:1 → 418
    2A0110; nucleoside transporter
Nucleotide Protein
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