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lrhA DNA-binding transcriptional dual regulator LrhA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946769, updated on 10-Oct-2024

Summary

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Official Symbol
lrhA
Official Full Name
DNA-binding transcriptional dual regulator LrhA
Primary source
ECOCYC:EG12123
Locus tag
b2289
See related
ASAP:ABE-0007555
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2283; genR
Summary
LysR family. [More information is available at EcoGene: EG12123]. LrhA, "LysR homologue A," regulates the transcription of genes involved in the synthesis of type 1 fimbriae . [More information is available at EcoCyc: EG12123].
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Genomic context

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Sequence:
NC_000913.3 (2405703..2406641, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene NADH:quinone oxidoreductase subunit B Neighboring gene NADH:quinone oxidoreductase subunit A Neighboring gene glutamate--pyruvate aminotransferase AlaA Neighboring gene dCMP phosphohydrolase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characteristics of the LrhA subfamily of transcriptional regulators from Sinorhizobium meliloti. Qi M, et al. Acta Biochim Biophys Sin (Shanghai), 2008 Feb. PMID 18235979
  2. The hexA gene of Erwinia carotovora encodes a LysR homologue and regulates motility and the expression of multiple virulence determinants. Harris SJ, et al. Mol Microbiol, 1998 May. PMID 9643539
  3. The Erwinia chrysanthemi pecT gene regulates pectinase gene expression. Surgey N, et al. J Bacteriol, 1996 Mar. PMID 8626286, Free PMC Article
  4. Mutations upregulating the flhDC operon of Escherichia coli K-12. Lee C, et al. J Microbiol, 2013 Feb. PMID 23456724
  5. LrhA as a new transcriptional key regulator of flagella, motility and chemotaxis genes in Escherichia coli. Lehnen D, et al. Mol Microbiol, 2002 Jul. PMID 12123461

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within DNA-templated transcription IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-binding transcriptional dual regulator LrhA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2405703..2406641 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416792.1 DNA-binding transcriptional dual regulator LrhA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416792.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376M4Z4, A0A5B9AL51, A0AAN3UFP7
    Conserved Domains (1) summary
    PRK15092
    Location:1 → 310
    PRK15092; DNA-binding transcriptional repressor LrhA; Provisional
Nucleotide Protein
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