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fbaB fructose-bisphosphate aldolase class I [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946632, updated on 3-Nov-2024

Summary

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Official Symbol
fbaB
Official Full Name
fructose-bisphosphate aldolase class I
Primary source
ECOCYC:G7129
Locus tag
b2097
See related
ASAP:ABE-0006941
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
dhnA; ECK2090
Summary
The typical class I aldolases of plants and animals have been throroughly studied Fructose-1,6-bisphosphate aldolases can be divided into two classes on the basis of their catalytic and structural properties. [More information is available at EcoCyc: G7129].
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Genomic context

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Sequence:
NC_000913.3 (2177512..2178564, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative tagatose-1,6-bisphosphate aldolase 2 chaperone Neighboring gene tagatose-1,6-bisphosphate aldolase 2 Neighboring gene putative transporter YegT Neighboring gene putative ADP-ribosylglycohydrolase YegU Neighboring gene putative sugar kinase YegV Neighboring gene putative DNA-binding transcriptional regulator YegW

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase. Thomson GJ, et al. Biochem J, 1998 Apr 15. PMID 9531482, Free PMC Article
  2. Novel kinetic and structural properties of the class-I D-fructose 1,6-bisphosphate aldolase from Escherichia coli (Crookes' strain). Baldwin SA, et al. Biochem J, 1978 Mar 1. PMID 348198, Free PMC Article
  3. Phosphate modification of fructose-1,6-bisphosphate aldolase in Escherichia coli. Babul J, et al. Biochem Biophys Res Commun, 1988 Mar 30. PMID 3281666
  4. Glucose metabolism in Escherichia coli and the effect of increased amount of aldolase. Babul J, et al. Biochemistry, 1993 May 4. PMID 8485146
  5. Comparison of the mechanisms of two distinct aldolases from Escherichia coli grown on gluconeogenic substrates. Scamuffa MD, et al. Biochim Biophys Acta, 1980 Aug 7. PMID 6996735

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables fructose-bisphosphate aldolase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables fructose-bisphosphate aldolase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol HDA PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane HDA PubMed 

General protein information

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Preferred Names
fructose-bisphosphate aldolase class I
NP_416600.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2177512..2178564 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416600.4 fructose-bisphosphate aldolase class I [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416600.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376M5Z9, A0A377DRU1, A0A5N3D5X6
    Conserved Domains (1) summary
    PRK09250
    Location:1 → 350
    PRK09250; class I fructose-bisphosphate aldolase
Nucleotide Protein
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