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bioC malonyl-acyl carrier protein methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945388, updated on 19-Sep-2024

Summary

Official Symbol
bioC
Official Full Name
malonyl-acyl carrier protein methyltransferase
Primary source
ECOCYC:EG10119
Locus tag
b0777
See related
ASAP:ABE-0002648
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0766
Summary
BioC is involved in an early, biochemically undefined step of biotin biosynthesis . bioC mutants require biotin for growth and appear to be blocked before the synthesis of pimeloyl-CoA . [More information is available at EcoCyc: EG10119].
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Genomic context

Sequence:
NC_000913.3 (811522..812277)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene adenosylmethionine-8-amino-7-oxononanoate aminotransferase Neighboring gene biotin synthase Neighboring gene 8-amino-7-oxononanoate synthase Neighboring gene dethiobiotin synthetase Neighboring gene UvrABC excision nuclease subunit B Neighboring gene putative transferase YbhK

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables carboxyl-O-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables carboxyl-O-methyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables malonyl-CoA methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biotin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within biotin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in methylation IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
malonyl-acyl carrier protein methyltransferase
NP_415298.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    811522..812277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415298.1 malonyl-acyl carrier protein methyltransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415298.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2X1QD91, A0A8S7BJY9
    Conserved Domains (1) summary
    PRK10258
    Location:1251
    PRK10258; biotin biosynthesis protein BioC; Provisional